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Impact of Fluid Resuscitation on Venous Congestion in Cardiac Critically-ill Patients

Impact of Fluid Resuscitation on Venous Congestion in Cardiac Critically-ill Patients

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07183397
Acronym
VExUS-CS
Enrollment
250
Registered
2025-09-19
Start date
2025-09-15
Completion date
2027-12-31
Last updated
2025-09-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac Anaesthesia, Cardiac and Aortic Surgery, Fluid Resuscitation, Venous Congestion

Brief summary

The objective of this study is to assess how fluid resuscitation, in the context of fluid responsiveness, affects the incidence and progression of systemic venous congestion in critically ill cardiac patients. Additionally, the study aims to evaluate the impact on clinical outcomes, with a particular focus on acute kidney dysfunction. This assessment will utilize the VExUS score in conjunction with comprehensive bedside echocardiographic evaluations.

Interventions

DIAGNOSTIC_TESTVExUS & Cardiac Ultrasound

The VExUS system provides a semi-quantitative assessment of systemic venous congestion by integrating ultrasound evaluations of the inferior vena cava diameter, hepatic vein flow, portal pulsatility, and renal venous flow, offering a practical and comprehensive bedside tool

Sponsors

Medical University of Vienna
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Age above 18 years * Admission to cardiac intensive care unit

Design outcomes

Primary

MeasureTime frameDescription
Venous congestion7 daysVenous congestion as assessed by the VExUS score at ICU admission, and on each of the first seven postoperative days.
Acute kidney injuryTwenty-eight daysAcute kidney injury (AKI), defined through the KDIGO criteria, within seven and twenty-eight days of ICU admission.

Contacts

Primary ContactPedro D Wendel Garcia, Dr. med.
pedro.wendelgarcia@meduniwien.ac.at+4369981577596

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026