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Prevalence and Clinical-Economic Aspects of Malnutrition in Rehabilitation

A Prospective Observational Study on the Prevalence of Malnutrition and Clinical-Economic Aspects of the Impact of Specialized Nutritional Care on the 3-month Outcomes of Patients at High Risk of Malnutrition Admitted to a Rehabilitation Hospital

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07183098
Enrollment
193
Registered
2025-09-19
Start date
2018-04-15
Completion date
2022-12-31
Last updated
2025-09-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malnutrition, Rehabilitation

Keywords

Rehabilitation, Dietitians, Healthcare costs, MUST-Malnutrition Universal Screening Tool, malnutrition, Nutritional care

Brief summary

The goal of this observational study is to learn about the clinical and economic aspects of specialized nutritional care in participiants at high risk of malnutrition (Malnutrition Universal Screening Tool-MUST equal or higher than 2) admitted to a rehabilitation hospital. The main questions it aim to answer are: * Does a specialized nutritional care lower hospital readmission rate at three months post-discharge in participiants at high risk of malnutrition admitted to a rehabilitation hospital? * Does a specialized nutritional care lower the number of emergency department admissions, number of general practitioner (GP) and outpatient visits, number of diagnostic tests and daily medication use and mortality rate in participiants at high risk of malnutrition admitted to a rehabilitation hospital? Participiants at high risk of malnutrition, three months after discharge were monitored through telephone interview about the hospital readmission and mortality rate, the number of emergency department admissions, GP and outpatient visits, diagnostic tests and daily medication use for treatment burden.

Interventions

OTHERParticipiants at high risk of malnutrition who received standard nutritional care

The overall clinical managment of people by ward's staff includes also nutritional care. Within 24-48 h after hospitalization, the ward's nursing staff screens people for nutritional risk using the Malnutrition Universal Screening Tool (MUST) tool. The attending ward's physician prescribes nutritional support and laboratory analyses in accordance with people's clinical needs and the underlying disease. Ward's physician cllinical judgement guides the decision to reassess and monitor the people's nutritional risk and status.

OTHERParticipiants at high risk of malnutrition who received specialized nutritional care

People referred to the Dietetic and Clinical Nutrition Service (DCNS) receive a structured, evidence-based diagnostic and therapeutic nutritional support. A dietitian performs a dietary assessment and the attending physicians of the DCNS prescribe a baseline set of laboratory analyses relevant for nutritional status. People referred to the DCNS are monitored regularly and systematically, daily or weekly according to the people's clinical condition and nutritional problems.

OTHER3 month-post discharge evaluation

Three months after discharge (follow-up), participiants of both groups were monitored through telephone interview to collect data regarding rate of hospital readmission, number of emergency department admissions, general practitioner visits, outpatient visits, diagnostic tests, daily medication use and survival.

Sponsors

Fondazione Don Carlo Gnocchi Onlus
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
50 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Admission to the rehabilitation hospital IRCCS Fondazione Don Carlo Gnocchi ONLUS, Florence * high risk of malnutrition (Malnutrition Universal Screening Tool-MUST equal or higher than 2)

Exclusion criteria

* age under 50 years; * oncological diagnosis associated with a poor six-month prognosis and/or with advanced or irreversible cachexia; * end-stage renal disease (dialysis); * people already participating in a cardiac rehabilitation program at the time of enrollment; * people with severe acquired brain injuries admitted for neurological rehabilitation.

Design outcomes

Primary

MeasureTime frameDescription
Hospital readmissions rate90 days post dischargeThe rate of hospital readmissions at three months post-discharge was computed as number of hospital readmissions from discharge to three-month follow-up.

Secondary

MeasureTime frameDescription
General practitioner visits rate90 days post-dischargeGeneral practitioner visits rate was computed as the number of general practitioner visits from discharge to three-month follow-up
Outpatient visits rate90 days post-dischargeThe outpatient visits rate was computed as the number of outpatient visits from discharge to three-month follow-up
Emergency department admissions rate90 days post-dischargeThe rate of emergency department admissions was computed as the number of emergency department admissions from discharge to three-month follow-up.
Daily medication rate90 days post-dischargeDaily medication rate is the number of drugs/day computed from discharge to three-month follow-up
Mortality rate90 days post-dischargeMortality rate was computed as the number of participiants dead from discharge to three-month follow-up
Diagnostic tests rate90 days post-dischargeThe diagnostic tests rate was computed as the number of diagnostic tests performed from discharge to three-month follow-up

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026