Ultrasound to Detect Splenomegally in Patients With Isolated Thrombocytopenia

Clinicopathologic Significance of Splenomegally in Adult Patients With Isolated Thrombocytopenia

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07182760

Enrollment

100

Registered

2025-09-19

Start date

2025-10-31

Completion date

2027-05-31

Last updated

2025-09-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Amegakaryocytic Aplasia, Autoimmune Diseases With Secondary ITP, Lymphoproliferative Disorder With Secondary ITP, Primary Immune Thrombocytopenic Purpura, Unilineage Myelodysplastic Syndrome ( Megakaryocyte Dysplasia)

Brief summary

Investigate prevalence of splenomegally in patients with isolated thrombocytopenia. Asess effect of splenomegally in clinical picture ,Complication, treatment response and disease outcome To explain possible causes of splenomegally in patients with isolated thrombocytopenia

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

* patients more than 18 years admitted with isolated thrombocytopenia due to primary Immune thrombocytopenic purpura amegakaryocytic aplasia Unilineage myelodysplastic syndrome ( megakaryocyte dysplasia) lymphoproliferative disorder with secondary ITP autoimmune diseases with secondary ITP Willingness to participate in the study Admitted patients or those who follow at hematology outpatients clinic

Exclusion criteria

EDTA induced pseudothrombocytopenia Platelet satellitism Drug induced thrombocytopenia Heparin induced thrombocytopenia / thrombosis syndrome post transfusion purpura Disseminated intravascular coagulopathy patients less than 18 years old patients with bicytopenia or pancytopenia Pregnancy \-

Design outcomes

Primary

Measure	Time frame	Description
Investigate prevalence of splenomegally in patients with isolated thrombocytopenia. Asess effect of splenomegally in clinical picture ,Complication, treatment response and disease outcome	Baseline	1. How many patients with isolated thrombocytopenia present with splenomegaly 2. Do patients with splenomegaly experience different complications compared to those without splenic enlargement 3. Is there a difference in treatment response between patients presenting with splenomegaly and those without splenic involvement

Contacts

Primary ContactKarim Ashraf, Resident

Karimazqal123@gmail.com+20

Outcome results