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Correlation Between the Midpalatal Suture Maturity and the Maxillary Third Molar Mineralization: a CBCT Study

Correlation Between the Midpalatal Suture Maturity and the Maxillary Third Molar Mineralization: a Cone Beam Computed Tomography Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07181707
Enrollment
200
Registered
2025-09-18
Start date
2026-01-01
Completion date
2026-03-26
Last updated
2026-04-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Maturation of the Midpalatal Suture and Maxillary Third Molar Mineralization in Healthy Individuals

Keywords

Molar, third, Cone Beam Computed Tomography, cranial suture, tooth calcification

Brief summary

Assessing the maturation of the mid-palatal suture is an essential criterion for orthodontic decision-making. However, from a CBCT according to Angelieri's classification , it remains difficult for the practitioner's untrained eye. As profile teleradiographs are almost routinely performed in orthodontic check-ups, numerous studies have looked for a correlation between the stage of maturation of the palatal suture and that of the cervical vertebrae. Some have also looked for a link with mineralization of mandibular third or second molars according to Demirjian's classification. These techniques would provide a reliable and reproducible method without the use of CBCT. In our study, the investigators will be looking for a correlation with mineralization of the maxillary third molar according to Nolla's classification. The latter has become common in practice and easy to apply on an orthopantomogram. This would simplify decision-making without the need for a CBCT, but by using the orthopantomogram which is already routinely performed during the assessment.

Detailed description

The study is a non-interventional (observational) research involving the human person, research on existing data (retrospective study). This study analyzes the maturation stage of the Midpalatal suture and the mineralization of the third left molar. This is a comparative retrospective study of radiographs in three dimensions before any orthodontic treatment to study a potential correlation. There is no control group but there are subgroups depending of the age of the patients.

Interventions

None listed

Sponsors

Central Hospital, Nancy, France
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
9 Years to 40 Years
Healthy volunteers
Yes

Inclusion criteria

* No previous orthodontic or orthopedic treatment * At least the maxillary third left molar * No skeletal disability

Exclusion criteria

* Previous maxillofacial trauma * Dentofacial deformities * Endocrinological pathologies with implications for maxillofacial growth • - Syndromes * History of maxillofacial or orthognathic surgery * History of orthodontic treatment * Incomplete data or incomplete CBCT * Maxillary third left molar fracture/cavity/other deterioratedation

Design outcomes

Primary

MeasureTime frameDescription
Maturation stages of the midpalatal sutureOne dayStages according to Angelieri et al.
Third molar calcificationOne dayCalcification's stages of the third left molar maxillary (from 0 to 10) according to Nolla.

Countries

France

Contacts

STUDY_DIRECTORBart VANDE VANNET, PhD

Central Hospital, Nancy, France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: May 1, 2026