Cognitive Abilities, Fasting State
Conditions
Brief summary
Objectives: The purpose of this study is to examine how meal timing in a one-meal-a-day (OMAD) regimen influences neurocognitive outcomes. Methods: Twelve cognitively active participants (academics, students, software engineers) will complete three randomized OMAD conditions, consuming a standardized isocaloric meal at 08:00, 12:30, or 18:00. ERPs will be recorded during a computerized Stroop task to evaluate peak amplitudes and latencies under congruent and incongruent conditions. Resting-state EEG will be measured under eyes-open and eyes-closed conditions. Behavioral performance on the Stroop task, including reaction time and accuracy, will also be assessed.
Interventions
OTHERone-meal-a-day (OMAD)
Arm Title: Morning Meal (08:00) Intervention: Other: One-meal-a-day (OMAD) Description: Participants consume a single isocaloric meal at 08:00. Arm Title: Midday Meal (12:30) Intervention: Other: One-meal-a-day (OMAD) Description: Participants consume a single isocaloric meal at 12:30. Arm Title: Evening Meal (18:00) Intervention: Other: One-meal-a-day (OMAD) Description: Participants consume a single isocaloric meal at 18:00.
Sponsors
Erzurum Technical University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
MALE
Age
20 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
Male, 20 to 45 years of age Right-handed Normal or corrected-to-normal vision Cognitively active individuals (academic staff, graduate students, or software/algorithm engineers) Regular sleep-wake schedule during the week preceding the experiment Ability to abstain from caffeine, alcohol, or psychoactive substances for at least 24 hours prior to each test session Body mass index between 18.5 and 30 kg/m²
Exclusion criteria
History of neurological, psychiatric, metabolic, or sleep disorders Current use of medications that affect the central nervous system Shift work or irregular sleep patterns (verified by sleep diary) Prior experience with one-meal-a-day dietary routines Body mass index below 18.5 or above 30 kg/m²
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Positive Peak Amplitude of Event-Related Potentials During Stroop - Congruent Trials | Day 1 Morning session (09:30-11:00, pre-meal) and Day 1 Afternoon session (14:30-16:00, ~6 hours post-meal). Each participant completes three separate test days (morning, midday, evening feeding), ≥48 hours apart. | Maximum voltage deflection (µV) within 250-450 ms after stimulus onset at CP1, CP2, Pz, P3, O1, and O2 electrodes, recorded during congruent Stroop trials using a 32-channel EEG system. |
| Latency of Positive Peak of Event-Related Potentials During Stroop - Congruent Trials | Day 1 Morning session (09:30-11:00, pre-meal) and Day 1 Afternoon session (14:30-16:00, ~6 hours post-meal). Each participant completes three separate test days (morning, midday, evening feeding), ≥48 hours apart. | Time point (ms) of maximum positive deflection within 250-450 ms after stimulus onset at CP1, CP2, Pz, P3, O1, and O2 electrodes. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Resting-State EEG Absolute Power (Eyes-Open and Eyes-Closed) | Day 1 Morning session (09:30-11:00, pre-meal) and Day 1 Afternoon session (14:30-16:00, ~6 hours post-meal). Each participant completes three separate test days (morning, midday, evening feeding), ≥48 hours apart. | Broadband spectral power (µV²) recorded at CP1, CP2, Pz, P3, O1, and O2 electrodes during standardized eyes-open and eyes-closed resting-state EEG. |
Countries
Turkey (Türkiye)
Outcome results
None listed