Effect of Dexmedetomidine Infusion on Post Anesthesia Discharge Time

Effect of Low Dose Intravenous Dexmedetomidine on Post Anesthesia Discharge After Day Case Breast Cancer Surgery

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07180810

Enrollment

Registered

2025-09-18

Start date

2023-09-05

Completion date

2025-08-20

Last updated

2025-09-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post Anesthesia Discharge Time in Patients of Breast Cancer Surgery

Keywords

Breast cancer surgery, Dexmedetomidine, Post anesthesia discharge time

Brief summary

A randomised control trial evaluating the effect of low dose dexmedetomidine infusion on post anesthesia discharge time in patients of day case breast cancer surgery compared with placebo infusion. The primary outcome was to compare the frequency of early discharge in each group.

Detailed description

A prospective Randomised control trial evaluating the effect of low dose dexmedetomidine infusion on post anesthesia discharge time in patients of day case breast cancer surgery compared with placebo infusion. The primary outcome was to compare the frequency of early discharge in each group. Early discharge was defined as within two hours. The sample size was of 82 female patients with a specific inclusion and exclusion criteria. Randomisation was done through computer software and the trial was double blinded. SPSS version 22 will be used for data analysis.

Interventions

DRUGDexmedetomidine infusion low dose

low dose dexmedetomidine infusion at rate 0.6mcg/kg/hour rate .

DRUGGroup B receiving normal saline

Normal saline infusion at rate 0.6mcg/kr/hour rate

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Caregiver)

Masking description

Double blinded study, all participants, and the care provider providing anesthesia to the participants were blinded

Intervention model description

Group A being administered low dose intravenous dexmedetomidine infusion vs Group B being admissions IV normal saline infusion at rate 0.6mcg/kg/hour rate

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 60 Years

Healthy volunteers

Inclusion criteria

* Age 18-60 yrs, ASA 1 and 2, elective breast cancer surgery

Exclusion criteria

* BMI greater than 35, CKD stage 3 or greater, known drug allergy to study drug, bradycardia, history of PONV, patients on antiepileptics

Design outcomes

Primary

Measure	Time frame	Description
Frequency of early discharge	120 minutes	post anesthesia discharge time within 2 hours

Countries

Pakistan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026