Hepatectomy, Liver Metastases, Liver Metastasis, Liver Resection, Non-colorectal Liver Metastases, Non-colorectal Liver Metastasis, Non-neuroendocrine Liver Metastases, Non-neuroendocrine Liver Metastasis
Conditions
Keywords
Non-colorectal non-neuroendocrine liver metastases, Liver metastases, Liver resection, Hepatectomy
Brief summary
The investigators designed this observational, retrospective, multicenter study including all patients who underwent surgery for non-colorectal liver metastases between January 2010 and December 2022, with the aim of establishing a series of recommendations for the treatment of liver metastases from various extrahepatic primary tumors
Interventions
None listed
Sponsors
Clinica Universidad de Navarra, Universidad de Navarra
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients scheduled for liver surgery due to non-colorectal liver metastases, regardless of the primary tumor origin, via open or minimally invasive approach
Exclusion criteria
* Patients undergoing surgery for colorectal liver metastases, emergency surgical interventions and patients younger than 18 years old.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Overall Survival | 5 years from liver resection | Time from the date of liver resection for non-colorectal metastases to death from any cause. Survival will be assessed for up to 5 years postoperatively |
| Progression-Free Survival | 5 years from surgery | Time from the date of liver resection for non-colorectal metastases to the date of documented disease progression or death from any cause, whichever occurs first. Patients without progression or death will be censored at the last follow-up |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Recurrence Pattern | Up to 5 years from liver resection | Distribution and characterization of tumor recurrence (hepatic, extrahepatic, or both) after liver resection for non-colorectal metastases. |
| Postoperative Morbidity Rate | 90 days from surgery | Incidence of any postoperative complications occurring within 90 days after liver resection, including but not limited to infections, bleeding, bile leaks, and other surgical complications, classified according to standard criteria. |
| R0 Resection Rate | At surgery | Proportion of patients achieving complete microscopic liver tumor resection (R0) during liver resection |
| Length of hospital stay | Perioperative/Periprocedural | Number of days from surgery to discharge following liver resection |
| Postoperative Mortality Rate | 90 days from surgery | Proportion of patients who die from any cause within 90 days following liver resection surgery. |
Outcome results
None listed