Intensive Care Unit Rehabilitation Protocols

Effects of Two Different Rehabilitation Protocols on Mobility, Functional Status, Muscle Parameters, and Hemodynamic Responses in Intensive Care Patients

Status

Active, not recruiting

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07179718

Acronym

ICU-Rehab

Enrollment

Registered

2025-09-18

Start date

2024-06-21

Completion date

2026-06-30

Last updated

2025-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Critical Illness, ICU Patients

Brief summary

The aim of this study was to investigate the effects of NMES combination applied in addition to bicycle ergometry on mobility, functional status, muscle strength and hemodynamic responses in ICU patients. Participants will: * Exercise training will be performed using the bicycle ergometer method, under the supervision of a physiotherapist, for 30 minutes a day for 5 consecutive days, at the earliest stage when the patient is clinically stable. * The other group will perform a 30-minute quadriceps muscle NMES session applied with a 4-channel electrical stimulator for 5 consecutive days in addition to the bicycle ergometer. * Evaluations for both groups will be made on the first day of the study (before starting the exercise training) and at the end of the fifth day (after the exercise training).

Interventions

DEVICEneuromuscular electrical stimulation

Neuromuscular electrical stimulation (NMES) is a treatment method in which electrical conduction via surface electrodes is used to stimulate muscle contraction.

DEVICEbicycle ergometer

Exercise training will be performed using the bicycle ergometer method, under the supervision of a physiotherapist, for 30 minutes a day for 5 consecutive days, at the earliest stage when the patient is clinically stable.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Age ≥ 18 years * Admitted to medical intensive care unit * Expected intensive care unit stay \> 48 hours * Hemodynamically stable

Exclusion criteria

* Severe neurological injury (e.g., acute stroke, spinal cord injury) * Terminal illness with palliative care decision * Severe orthopedic limitations preventing mobilization * Pregnancy

Design outcomes

Primary

Measure	Time frame	Description
Change in Perme Intensive Care Unit Mobility Score over 5 days	1st and 5th day of 5-day physiotherapy and rehabilitation after the patient is clinically stable	The total score ranges from 0 to 32 points, with higher scores indicating better mobility and greater independence.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026