Primary Stability and Peri-implant Outcomes of Short Implants in Post-extraction Single-tooth Sites

Primary Stability and Peri-implant Outcomes of Short Implants in Post-extraction Single-tooth Sites: a Randomized Controlled Trial.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07177521

Enrollment

Registered

2025-09-17

Start date

2025-01-10

Completion date

2026-08-10

Last updated

2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Edentulous Jaw, Toothless Mouth, Tooth Loss

Brief summary

The placement of short implants in post-extraction sockets is a valuable option when residual bone height is limited, minimizing morbidity and treatment time. The management of the peri-implant gap and soft tissues may influence primary stability, hard/soft tissue remodeling, and implant success.

Interventions

PROCEDUREInsertion of implants in post-extraction tooth

Two widely used approaches include: 1. Socket grafting with a fully resorbable synthetic biomaterial (β-tricalcium phosphate + calcium sulfate). 2. Socket grafting with a xenograft and a custom Sealing Socket Abutment (SSA) with a concave emergence profile. No randomized controlled trials have yet compared these protocols with integrated outcomes including resonance frequency analysis, peri-implant health indices, radiographic bone level changes, and digital intraoral scanning (IOS)-based morphometric analysis.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

18 Years to 75 Years

Healthy volunteers

Yes

Inclusion criteria

* Age ≥18 years. * Single-tooth post-extraction sites requiring immediate implant placement in posterior regions (premolars/molars) or selected anterior sites. * Planned short implant (≤7-8 mm length, 3.5-5.0 mm diameter). * Adequate oral hygiene, no active periodontal disease. * Written informed consent.

Exclusion criteria

* Heavy smoking (\>20 cigarettes/day). * Uncontrolled diabetes or systemic conditions affecting bone healing. * Current bisphosphonate/antiresorptive therapy. * Immunosuppression, pregnancy. * Poor oral hygiene or acute infection at site. * Severe bone dehiscence preventing primary stability.

Design outcomes

Primary

Measure	Time frame	Description
Primary stability	1 month	To compare the primary stability (ISQ values at implant insertion) of short implants placed in post-extraction sockets using the two grafting protocols.

Secondary

Measure	Time frame	Description
Clinical Indices	12 months	To assess peri-implant health indices (PD)

Countries

Italy

Contacts

CONTACTGiuseppe D'Albis, Dr

giuseppe.dalbis@uniba.it+393495103642

CONTACTSaverio Capodiferro

saverio.capodiferro@uniba.it

PRINCIPAL_INVESTIGATORGiuseppe D'Albis, Dr

University of Bari Aldo Moro

STUDY_CHAIRSaverio Capodiferro, Prof