Deep Brain Stimulation, Pain Management, Parkinsons Disease, Regional Anesthesia
Conditions
Keywords
Pectoserratus block, Interpektoral block, Deep brain stimulation, Awake surgery
Brief summary
Parkinson's disease is a chronic and progressive neurodegenerative disease that affects the central nervous system, particularly impairing movement control. It is associated with the loss of dopamine-producing cells in the brain and typically occurs in middle age and beyond. Deep brain stimulation (DBS) is considered when symptoms of Parkinson's disease, such as tremors, slowed movements, and muscle rigidity, are not adequately controlled with medications. Selected patients with severe symptoms that do not respond to medical treatment are generally considered for this treatment. Battery revision surgeries can be performed under general anesthesia or regional anesthesia. Patients undergoing general anesthesia should be cautious about the potential complications of general anesthesia, while those undergoing regional anesthesia should be cautious about the local anesthetic systemic toxicity. Because each method has its own advantages, the choice of anesthesia may vary. This study aimed to compare postoperative analgesic efficacy and patient satisfaction in patients who underwent surgery under general anesthesia or sedation-assisted battery replacement under regional anesthesia. Both anesthesia methods are routinely used in Parkinson's disease patients undergoing battery replacement.
Interventions
PROCEDUREPatients who underwent surgery under general anesthesia
Patients undergoing surgery under general anesthesia will undergo general anesthesia induction. During the skin closure, patients received 50 mg of dexketoprofen. Additionally, a paracetamol dose of 1 g every 8 hours and a dexketoprofen dose of 50 mg twice daily were administered intravenously for multimodal analgesia.
PROCEDUREPatients who underwent surgery under regional anesthesia
25 cc (15 cc 0.5% bupivacaine + 5 cc 2% lidocaine + 5 cc isotonic) local anesthetic solution is prepared. 10 cc of the medication is administered into the interpectoral plane, and 15 cc into the pectoserratus plane. During the skin closure, patients received 50 mg of dexketoprofen. Additionally, a paracetamol dose of 1 g every 8 hours and a dexketoprofen dose of 50 mg twice daily were administered intravenously for multimodal analgesia.
Sponsors
Ankara Etlik City Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
40 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
* Those aged 40-85 * Those with an ASA score of I-II-III * Those with a body mass index (BMI) between 18-30
Exclusion criteria
* Those under 40 and over 85 * Those with an ASA score of IV or higher * Those with a BMI of under 18 and over 30
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Pain score | up to 24 hours | Pain will be assessed using a visual analog scale from 0 mm (no pain) to 100 mm (worst pain) at rest and when coughing. Pain assessment will be made at 0, 1, 6, 12, 18, and 24 hours after surgery. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Patient Satisfaction | postoperative 24th hour | Patient satisfaction will be evaluated using a Likert scale.Evaluation will be made using a 5-point Likert scale (1= I am not satisfied at all - 5= I am very satisfied). |
| Need for additional analgesics | postoperative 24th hour | Additional analgesic need will be assessed |
Countries
Turkey (Türkiye)
Contacts
Primary Contactİbrahim MD Topcu, MD
Backup ContactMusa MD Zengin
Outcome results
None listed