Overactive Bladder Syndrome
Conditions
Keywords
overactive bladder, minimal clinically important difference, urinary incontinence, quality of life, ROC curve
Brief summary
The goal of this study was to determine the Minimal Clinically Important Difference (MCID) for the Overactive Bladder Questionnaire-Version 8 (OAB-V8) and the International Consultation on Incontinence Questionnaire- Short Form (ICIQ-SF) in people with Overactive Bladder Syndrome (OAB).
Detailed description
104 patients with OAB will receive common behavioral therapy and transcutaneous posterior tibial nerve stimulation (TPTNS) for 12 weeks. OAB-related symptoms and quality of life (QoL) will be assessed with the OAB-V8 and ICIQ-SF baseline and post-intervention. The receiver operating characteristic (ROC) analysis and the Gamma coefficient will be employed to determine sensitivity.
Interventions
OTHERBehavioral therapy and transcutaneous posterior tibial nerve stimulation
Behavioral therapy included appropriate fluid intake, bladder training, habit training, pelvic floor muscle exercises (Kegel exercises), prompted voiding, and scheduled voiding. TPTNS will be applied in a biphasic square waveform with a frequency of 20 Hz and 200 cycles/sec in 30-minute sessions. The current intensity will be varied between 0.5-20 mA according to the patient's pain threshold.
Sponsors
Artvin Coruh University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
In this prospective study, one treatment group was formed to receive behavioral therapy and transcutaneous posterior tibial nerve stimulation (TPTNS).
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* individuals diagnosed with urge and mixed urinary incontinence symptoms or with OAB symptoms only (no history of urinary incontinence), * women over 18 years of age.
Exclusion criteria
* patients who did not give consent to participate in the study, * not understanding the instructions given by the researcher, * pregnancy or planning a pregnancy in the near future, * urinary tract infection or kidney stones, * pelvic organ prolapse of grade II or higher, * stress-type urinary incontinence, * neurogenic bladder, * use of a pacemaker, * epilepsy, * peripheral neuropathy.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Overactive Bladder Questionnaire-Version 8 (OAB-V8) | Baseline | On this scale, which ranges from 0 to 40 points, higher scores are associated with greater symptom severity. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| International Consultation on Incontinence Questionnaire- Short Form (ICIQ-SF) | Baseline | The total score of the scale ranges from 0 to 21, with higher scores indicating more severe symptoms. It measures the frequency, severity, and impact of OAB through three main questions. An additional open-ended question allows patients to describe their symptoms. |
Countries
Turkey (Türkiye)
Contacts
PRINCIPAL_INVESTIGATORZeynep Yıldız Kızkın
Artvin Coruh University
Outcome results
None listed