Sedentary Middle Age and Older Aged Adults
Conditions
Brief summary
Alzheimer's disease and related dementias are a public health crisis impacting individuals across the world. In the United States, adults living in rural areas face an elevated risk for cognitive impairment mainly due to disparities in care, higher sedentary behavior, and reduced education. This project proposes to assess the impact of a remotely delivered exercise program (i.e., RemoteEx+) through a smartphone application. The app is programmed by our team and provides video demonstrations of exercises, workout regimes, motivational messaging, and weekly ADRD risk reduction education. The project aims to assess with a pre/post design the following aims: * Aim 1. Assess the RemoteEx+ intervention exercise adherence, efficacy, enjoyment, and quality of life. We hypothesize that rural adults will report high exercise adherence (80% of session adherence), efficacy (\>50% on Self Efficacy for Exercise), and enjoyment (\>5.0 on Intrinsic Motivation Inventory - Interest / Enjoyment Subscale) and that these variables will be positively correlated with quality of life scores (36-Item Short Form Health Survey \[SF-36\]) * Aim 2. Determine the impact of a technology-driven exercise program on blood pressure and functional mobility associated with dementia risk. We hypothesize that the exercise program will result in improvements in blood pressure and functional mobility (2-minute step test and 30-second chair rise test) and that participants with high exercise adherence will see the greatest improvements in biomarkers associated with reduced dementia risk. * Aim 3. Reduce health disparities among rural-dwelling Nebraska and Kansas residents. We hypothesize that RemoteEx+ will reduce barriers to exercise (Barriers to Being Active Quiz and improve knowledge surrounding dementia and modifiable risk factors (Dementia Knowledge Assessment Tool - Version 2 \[DKAT2\]) that will result in fewer lifestyle-related health disparities for the communities involved in this study. The results from this project will inform whether RemoteEx+ has an impact on the stated outcomes above for adults living in rural areas.
Interventions
BEHAVIORALRemoteEx+ Programming
The exercise program will include video instruction for all exercises, motivational cues, and ADRD risk education throughout the 16-week exercise program to encourage exercise adherence. RemoteEx+ is optimized to enhance exercise knowledge surrounding dementia risk factors to facilitate ADRD risk reduction and overall health improvement. The purpose of this study is to investigate the efficacy of RemoteEx+ on health outcomes associated with dementia risk in underactive rural adults.
Sponsors
Creighton University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
40 Years to 85 Years
Healthy volunteers
Yes
Inclusion criteria
* Age 40-85 years * Characterized as underactive by the Telephone Assessment of Physical Activity (TAPA)50 * Self-reported proficiency in English * Own a smartphone and willing to download an application * Primary care provider clearance to participate for those who do not pass the PAR-Q+51 * Live in a rural area (Rural-Urban Commuting Area \[RUCA\] Codes) 52
Exclusion criteria
* Contraindications to high-intensity exercise * Cognitive impairment (\<19 on the Telephone Montreal Cognitive Assessment \[MoCA\]) * Neurodegenerative or acute neurological diagnoses (e.g., Parkinson's disease, stroke, traumatic brain injury) * Orthopedic surgery or injuries in the last 6 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Systolic Blood Pressure | Baseline and Week 16 |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Cardiovascular Endurance | Baseline and Week 16 | 2-Minute Step Test |
| Lower Extremity Strength | Baseline and Week 16 | 30-second chair rise test |
| Exercise Adherence | Baseline and Week 16 | % of sessions completed over the 16-week program |
| Exercise Efficacy | Baseline and Week 16 | Self Efficacy for Exercise (SEE) Scale (points) |
| Quality of Life Improvement | Baseline and Week 16 | 36-Item Short Form Health Survey |
| Barriers to Being Active | Baseline and Week 16 | Barriers to Being Active Quiz |
| Knowledge of dementia | Baseline and Week 16 | Dementia Knowledge Assessment Tool |
Countries
United States
Contacts
Primary ContactRashelle Hoffman, PT, DPT, PhD
Backup ContactErin Blocker, PhD
Outcome results
None listed