Pulmonary and Extra- Pulmonary Tuberculosis (TB)
Conditions
Brief summary
Tuberculosis is a major cause of ill health and one of the leading causes of death worldwide. Early, rapid and accurate diagnosis of all TB patients and prompt treatment with any form of drug-susceptible or drug resistant TB is fundamental. Identifying the pattern of drug resistance will ensure that the most effective therapy can be selected. The aim of this study is to assess the prevalence and patterns of drug resistance of mycobacterium tuberculosis and to detect the possible risk factors associated with resistant cases.
Interventions
None listed
Sponsors
Sohag University
Study design
Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
12 Years to No maximum
Inclusion criteria
* geneXpert positive patients in pulmonary and extrapulmonary cases
Exclusion criteria
* age below 12 years
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Detection of number of cases resistant to Rifampicin and other anti- TB drugs | within 6 months of starting treatment | Using of GeneXpert (MTB/RIF) and Xpert (MTB/XDR) assays to detect resistance to Rifampicin and other anti -TB drugs among TB positive cases |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Detection of common Risk factors associated with resistant cases | within 6 months of starting treatment coarse | collection of (in common) data among cases to detect risk factors associated with drug resistance e.g is drug resistance more common in diabetic patients?, is resistance more common among drug addict patients? , also is there common co-morbid conditions among resistant cases |
Countries
Egypt
Contacts
Primary ContactOmnia Abdelazeem Zahran
Outcome results
None listed