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Comparison of ESP, SAP and SPSIP Blocks on VATS'

Comparison of the Analgesic Efficacy of Erector Spinae Plane Block, Serratus Anterior Plane Block, and Serratus Posterior Superior Intercostal Plane Block on Postoperative Pain in Patients Undergoing Video-Assisted Thoracoscopic Surgery

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07165873
Enrollment
45
Registered
2025-09-10
Start date
2023-07-01
Completion date
2024-08-15
Last updated
2025-09-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Pain Management

Keywords

erector spinae plane block, serratus anterior plane block, serratus posterior superior intercostal plane block, video-assisted thoracoscopic surgery, postoperative pain

Brief summary

This study aimed to compare erector spinae plane block (ESPB), serratus anterior plane block (SAPB), and serratus posterior superior intercostal plane block (SPSIPB) to determine the most suitable technique for maintaining postoperative analgesia in video-assisted thoracoscopic surgeries (VATS).

Detailed description

Patients were randomly allocated into three groups: ESPB, SAPB, and SPSIPB. All patients received postoperative paracetamol and dexketoprofen, and intravenous tramadol hydrochloride was administered via patient-controlled analgesia. Postoperative static and dynamic VAS scores, total tramadol consumption, side effects, and the need for additional analgesia were monitored and recorded at regular intervals. Primary outcome was VAS scores and secondary outcome was total tramadol consumption. Block Techniques All blocks were performed following surgical closure, prior to extubation, with the patient in lateral decubitus and the skin prepared with 10% povidone-iodine. ESPB was performed in 15 patients. An ultrasound (USG) probe was placed in a sagittal orientation at the T5 level, 3 cm lateral to the midline, to visualize the transverse process. The trapezius, rhomboid major, and erector spinae muscles were identified. Using an in-plane technique, a needle was advanced cranio-caudally through these muscles until it reached the transverse process. After negative aspiration, 30 mL of 0.25% bupivacaine was injected deep to the erector spinae muscle. SAPB: The latissimus dorsi and serratus anterior muscles were identified at the midaxillary line at the 4th-5th rib level in a longitudinal parasagittal orientation. A needle was advanced from caudal to cranial using an in-plane approach, first targeting the plane between the latissimus dorsi and serratus anterior, and then deep to the serratus anterior. After negative aspiration, 10 mL was injected into the superficial plane and 20 mL into the deep plane, for a total of 30 mL of 0.25% bupivacaine. SPSIPB: The USG probe was placed 2-3 cm medial to the scapular spine to visualize the trapezius, rhomboid major, and serratus posterior superior muscles. At the level of the 2nd-3rd ribs, a needle was advanced into the plane between the serratus posterior superior muscle and the rib. After confirming negative aspiration, 30 mL of 0.25% bupivacaine was injected. All blocks were performed unilaterally, targeting the surgical hemithorax. Postoperative Analgesia and Assessments Twenty minutes before extubation, all patients received 1 g IV paracetamol and 50 mg IV dexketoprofen. In the recovery room, patient-controlled analgesia (PCA) with IV tramadol hydrochloride was initiated (4 mg/mL concentration, 10 mg bolus, 20-minute lockout, maximum 3 boluses/hour). Postoperative VAS scores (static at rest and dynamic during movement or coughing) were recorded at 0, 1, 6, 12, 18, and 24 hours. The first VAS assessment (0 hour) was performed when the patient achieved an Aldrete score of 9. If VAS ≥ 4, an additional 1 g IV paracetamol (maximum 3 g/day) was administered. Additional analgesic consumption was recorded. Side effects such as nausea, vomiting, and pruritus were documented.

Interventions

PROCEDUREErector Spinae Plane Block

30 mL of 0.25% bupivacaine was injected deep to the erector spinae muscle.

10 mL was injected into the superficial plane and 20 mL into the deep plane, for a total of 30 mL of 0.25% bupivacaine.

PROCEDURESerratus posterior superior intercostal plane block

30 mL of 0.25% bupivacaine was injected into the plane between the serratus posterior superior muscle and the rib.

Sponsors

Cumhuriyet University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Forty-five adult patients scheduled for elective wedge resection or biopsy under VATS, classified as American Society of Anesthesiologists (ASA) physical status I-III, were enrolled after providing written informed consent.

Exclusion criteria

* ASA class IV or higher, * morbid obesity (BMI \> 40 kg/m²), * body weight ≤ 50 kg, * skin infection at the block site, * refusal to participate, * inability to cooperate during postoperative pain assessment, * conversion to open surgery, * preexisting pain, * known allergy to any study medication, * coagulopathy.

Design outcomes

Primary

MeasureTime frameDescription
Visual analogue scale (VAS) scorepostoperative 24 hoursThe Visual Analogue Scale (VAS) measures pain intensity. The VAS consists of a 10 cm line, with two end points representing 0 ('no pain') and 10 ('pain as bad as it could possibly be').

Secondary

MeasureTime frameDescription
Total tramadol consumptionpostoperative 24 hoursPostoperative total analgesic (tramadol) need was recorded as milligram in unit.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026