Skip to content

Pilot Study to Evaluate the Effect of Transcendental Meditation on Telomere Activity and Well-Being Among Nurse Managers

Pilot Study to Evaluate the Effect of Transcendental Meditation on Telomere Activity and Well-Being Among Nurse Managers

Status
Enrolling by invitation
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07165795
Enrollment
30
Registered
2025-09-10
Start date
2025-05-18
Completion date
2027-05-31
Last updated
2025-09-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Meditation

Keywords

nurse manager, well-being, telomere, meditation

Brief summary

The objective of this study is to evaluate the impact of a health and coping strategy (Transcendental Meditation, or TM) on Telomere Length and Telomerase Activity (known markers of physiological and psychological stress and aging), Perceived Stress, Work Life Balance, Flourishing, Power as Knowing Participation in Change, and Burnout, among nurse managers. Aim 1: To evaluate the effects of TM compared to usual care delayed instruction on TL and TA. Aim 2: To evaluate the effects of TM compared to usual care delayed instruction on work life climate, flourishing, perceived stress, burnout, and power as knowing participation in change.

Interventions

Standard TM instruction by certified TM teachers, including 4 days of initial training (60-90 min/day), then follow-up sessions (60-90 min) every 2-4 weeks.

Sponsors

Florida Atlantic University
CollaboratorOTHER
Sarasota Memorial Health Care System
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE

Intervention model description

This study is a two-group randomized clinical trial (intervention and control groups) pilot study consisting of 30 nurse managers, with 15 nursing managers randomly assigned to each group.

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Nurse managers within the Sarasota Memorial Health Care System (SMHCS); * Stable for at least two months on any prescribed medications (for example, anti-anxiety or anti-depressant medications)

Exclusion criteria

* prior instruction in the TM technique

Design outcomes

Primary

MeasureTime frameDescription
Telomere Lengthbaseline, 1-month, 4-monthsT/S ratio; processed by UCSF Blackburn Labs SOP #104D
Telomerase Activitybaseline, 1-month, 4-months(# positive copies/10,000 input cells) ; processed by UCSF Blackburn Labs SOP #104D

Secondary

MeasureTime frameDescription
Perceived Stress Scale-10 (PSS10)baseline, 1-month, 4-months(Cohen, 1988); measures the perception of stressful thoughts and feelings in preceding month; responses range from 0-40 with higher scores indicating higher levels of stress.
Work-Life Climate Scalebaseline, 1-month, 4-months(Sexton, et al., 2017); measures work/life balance; responses range from 0-4; survey scores range 0-32, with lower scores reflecting better work/life balance.
Power as Knowing Participation in Change (PKPCT)baseline, 1-month, 4-monthsBarrett (1983, 1984, 2010); Scores range from 48-336 in four subscales with higher scores indicating higher levels of perceived power.
Maslach Burnout Inventory Human Services Survey for Medical Personnelbaseline, 1-month, 4-months(Maslach & Jackson, 1984); Consists of three subscales: Emotional Exhaustion (9-items, score range 0-54, higher scores indicate more emotional exhaustion); Depersonalization (5-items, score range 0-18, higher scores indicate more depersonalization); and Personal Accomplishment (8-items, score range 0-48, higher scores indicate higher level of personal accomplishment).
Secure Flourishing Index, SFIbaseline, 1-month, 4-months(Weziak-Bialowolska et al., 2019); measures multidimensional well-being; survey scores range from 0-120, with higher scores reflecting a higher level of flourishing.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026