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Nicotine Replacement Therapy Prescribing and Lung Cancer Screening in Hospitalized Patients

Increasing Nicotine Replacement Therapy Prescribing and Lung Cancer Screening in Hospitalized Patients Using an Innovative Non-Interruptive Alert Within the Electronic Health Record Provider Note

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07164404
Enrollment
220
Registered
2025-09-10
Start date
2025-11-17
Completion date
2026-09-01
Last updated
2026-05-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tobacco Use Disorder

Brief summary

Investigators are evaluating an EHR-based, non-interruptive alert to increase NRT prescribing in the hospital and at discharge for hospitalized patients. Investigators will investigate two randomized groups of resident physicians to evaluate their prescribing behaviors when the tool is introduced.

Detailed description

Efforts to decrease cancer-related morbidity and mortality include increasing smoking cessation, however smoking remains prevalent. Classically, alerts within the electronic health record (EHR) are implemented to address gaps in care, yet studies suggest typical EHR alerts are often overridden and ignored. In this study, the investigators aim to decrease the incidence and burden of disease by including hospitalists as part of the multidisciplinary care team by implementing and evaluating a novel non-interruptive EHR alert embedded within a provider note as a tool to increase prescription of nicotine replacement therapy to patients who smoke upon admission to and discharge from the hospital. Investigators will investigate two randomized groups of resident physicians to evaluate their prescribing behaviors when the tool is introduced.

Interventions

EHR embedded alert into the admission note template, where it automatically inserts smoking history, prompts NRT prescribing in the hospital, and offers referral to outpatient follow up.

Sponsors

Medical University of South Carolina
Lead SponsorOTHER
South Carolina Clinical & Translational Research Institute (SCTR)
CollaboratorUNKNOWN

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Patients Inclusion Criteria: * Hospitalized patients admitted to a General Medicine Service at MUSC Charleston * Identified as actively smoking tobacco via nursing admission screening * Admitted by a resident physician participating in the study (as indicated by the H\&P note)

Exclusion criteria

• None Resident Physicians: Inclusion Criteria: • Internal medicine resident physicians rotating on the hospitalist service at MUSC Health Charleston

Design outcomes

Primary

MeasureTime frame
Nicotine Replacement Therapy (NRT) prescribing rates during hospitalizationDuring hospitalization, assessed from admission to discharge (average of 3-7 days)
Nicotine Replacement Therapy (NRT) prescribing rates at dischargeDuring hospitalization, assessed from admission to discharge (average of 3-7 days)
Rate of referral to outpatient tobacco cessation clinicDuring hospitalization, assessed from admission to discharge (average of 3-7 days)

Countries

United States

Contacts

PRINCIPAL_INVESTIGATOREllen Esposito, MD

Medical University of South Carolina

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: May 9, 2026