Intraoperative Perfusion Index and Mortality

Association Between Intraoperative Perfusion Index and Mortality

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07164339

Enrollment

425000

Registered

2025-09-10

Start date

2024-12-18

Completion date

2025-10-31

Last updated

2025-09-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemodynamic, Intraoperative Hemodyamic Monitoring, Perfusion Index

Brief summary

This study will use routinely collected perioperative data to examine the relationship between intraoperative perfusion index and postoperative outcomes, including mortality.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Inclusion criteria

* Patients above 18 years of age who underwent general anesthesia for non-cardiac surgery of any type

Exclusion criteria

* No registration of intraoperative perfusion index or no information on vital status 30 days after surgery

Design outcomes

Primary

Measure	Time frame
All-cause mortality	30 days from time of surgery

Secondary

Measure	Time frame	Description
Composite Adverse Outcome	30 days from time of surgery	Proportion of participants who experience ≥1 of the following within 30 days after index surgery: 1. Postoperative admission to the intensive care unit 2. Reoperation (within 30 days) 3. Prolonged length of stay, defined as length of stay falling within the highest (75th-100th) percentile for the patient's surgical category 4. Acute kidney injury according to Kidney Disease: Improving Global Outcome (KDIGO) criteria (≥1.5-fold increase from baseline within 7 days after surgery or 0.3 mg dl-1 increase within 48 h)
Postoperative ICU Admission	30 days from date of surgery	Any ICU admission occurring after index surgery and within 30 days.
Reoperation	30 days from date of surgery	Any return to the operating room within 30 days of index surgery.
Prolonged Length of Stay (LOS)	Through hospital discharge (max. 6 months from surgery date)	Proportion of participants whose index-hospitalization LOS (days from surgery to discharge) falls in the 75th-100th percentile for their surgical category, determined from the study cohort distribution and assessed at discharge.
Acute Kidney Injury	30 days from date of surgery	AKI defined by KDIGO criteria (≥1.5× baseline serum creatinine within 7 days or ≥0.3 mg/dL increase within 48 h) occurring within 30 days of surgery.

Countries

Denmark

Outcome results