Bone Regeneration, Periodontal Intrabony Defects
Conditions
Brief summary
The aim of the study is to evaluate osseous regenerative efficacy of eggshell derived nanohydroxyapatite in comparison with hydroxyapatite The test group includes patients with intrabony defects where flap surgery will be performed & Eggshell derived nano hydroxyapatite (ESnHA) is placed.
Detailed description
Experimental : Main treatment group Eggshell derived nano hydroxyapatite is placed into defect site Comparator : In patients allocated to control group, only Hydroxyapatite is placed.
Interventions
OTHEREggshell derived nano hydroxyapatite
Eggshell derived nano hydroxyapatite has high solubility and allows faster integration & replaces with osseous tissue
OTHERHydroxyapatite
Hydroxyapatite has similar chemical composition with crystalline structure of native bone
Sponsors
Dr R Viswa Chandra
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 55 Years
Healthy volunteers
No
Inclusion criteria
Presence of Two-walled or three-walled intrabony defects & Probing pocket depths (PPD) of \>5mm after initial therapy Systemically healthy male and female patients of age \>18 years
Exclusion criteria
Medically compromised patients Pregnant women, Heavy smokers, and Patients who underwent radiotherapy or chemotherapy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| RVG | 3months & 6months | Radiovisiography will be used to assess bone regeneration achieved post operatively |
| Probing Depth | 3 months & 6months | — |
| Clinical Attachment Level | 3 months & 6 months | — |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Full mouth Plaque index | 3 months & 6 months | Full mouth plaque index was measured using Turesky modification of the Quigley-Hein Index at baseline, 3 months and 6 months |
| Full mouth Gingival index | 3 months & 6 months | Full mouth gingival index was measured using Loe & Silness Index at baseline, 3 months and 6 months |
Countries
India
Outcome results
None listed