Effects of Multiple Interventions on Under-Five Diarrhea

Effects of Maternal Handwashing Education and Household Water Chlorination on Diarrheal Disease Among Under-Five Children in Central Ethiopia Using RCT

Status

Not yet recruiting

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07158632

Enrollment

840

Registered

2025-09-08

Start date

2025-09-08

Completion date

2025-12-24

Last updated

2025-09-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diarrheal Diseases

Keywords

central Ethiopia, Diarrhea, Ethiopia, Multiple Interventions

Brief summary

Diarrhea is the leading cause of death, especially in developed nations. Though there are effective interventions, diarrhea remains the leading cause of death among children in Ethiopia

Detailed description

Diarrheal disease is the major cause of child morbidity and mortality in low-income countries, including Ethiopia. Diarrhea is more common in areas with a lack of water sanitation and hygiene. Even though there are available effective interventions, diarrhea remains the major cause of child morbidity and mortality in Ethiopia. Therefore, the aim of this study is to give up-to-date information on multiple interventions that reduce diarrheal disease.

Interventions

BEHAVIORALhandwashing education

Arm A: This arm receive handwashing education using social and behavioral change communication

BEHAVIORALwater chlorination

Arm B: This arm receives water chlorination intervention

BEHAVIORALcombined intervention

Arm C: This arm receives combined handwashing and water chlorination intervention

Study design

Allocation

RANDOMIZED

Intervention model

FACTORIAL

Primary purpose

PREVENTION

Masking

DOUBLE (Subject, Outcomes Assessor)

Intervention model description

The study contains four arms; these are handwashing education arm, water chlorination arm, combination arm, and control arm

Eligibility

Sex/Gender

ALL

Age

6 Months to 59 Months

Healthy volunteers

Inclusion criteria

* a child age from 6 to 59 months

Exclusion criteria

* severely ill mother, households that receive treated water

Design outcomes

Primary

Measure	Time frame
Incidence of diarrhea among under-five children	At baseline and to four-month follow-up

Secondary

Measure	Time frame	Description
Adherence of interventions	Up to four-month follow-up	percentage of soap availability near toilet and residual chlorine in drinking water

Countries

Ethiopia

Contacts

Primary ContactMelaku Tesfaye PhD Candidate, MPH

tesfayemelaku96@gmail.com=+251916141771

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026