Obesity (Disorder)
Conditions
Keywords
heat therapy, insulin resistance, arterial stiffness, blood pressure, obesity, sauna, vascular health, cardiovascular, metabolic function
Brief summary
This is a clinical trial to determine if 30 sessions of far infrared sauna bathing can improve cardiovascular and metabolic function in adults with obesity.
Detailed description
Obesity can increase the risk for cardiovascular and metabolic diseases. Lifestyle interventions are needed to reduce this risk. Far infrared saunas are one form of heat therapy that may help reduce these risks, however, there is limited research within a population with obesity. It is hypothesized that repeated far infrared sauna bathing will improve cardiovascular and metabolic function in adults with obesity.
Interventions
OTHERHeat therapy
30 sessions of far infrared sauna bathing (45-60C) for up to 45 min
Sponsors
University of Oregon
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
NONE
Intervention model description
Time control versus heat therapy group
Eligibility
Sex/Gender
ALL
Age
18 Years to 59 Years
Healthy volunteers
No
Inclusion criteria
* BMI between 30-45 kg/m2
Exclusion criteria
* Diagnosed diabetes * Greater than stage 2 hypertension * Coagulopathies * Allergies to lidocaine * Medications affecting blood pressure * Blood clotting, and blood sugars * Smoker * Pregnant * Desiring to become pregnant in the near future * Breastfeeding * BMI less than 30 * BMI greater than 45 kg/m2 * Exercising \> 120 min/week * Taking medications (other than hormone contraceptives) * Not willing to stop taking medications (other than hormone contraceptives) for 24 hours before testing days
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Blood pressure change | 10 weeks | Change in systolic and diastolic blood pressures after 30 sessions of Intervention |
| Blood glucose | 10 weeks | Change in plasma glucose levels after Intervention |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Arterial stiffness reduction | 10 weeks | Change in Carotid-femoral Pulse Wave Velocity (m/s) after Intervention |
| Serum insulin | 10 weeks | Change in serum insulin levels after Intervention |
Countries
United States
Contacts
CONTACTChristopher T Minson, PhD
CONTACTJohn R Halliwill, PhD
PRINCIPAL_INVESTIGATORChristopher T Minson, PhD
University of Oregon
Outcome results
None listed