Eosinophilic Esophagitis (EoE)
Conditions
Brief summary
Evaluating swallowing food with surface electromyography (EMG) machine in patients with Eosinophilic Esophagitis
Detailed description
Evaluating surface electromyography (sEMG) assessment of swallowing and bolus preparation in patients with Eosinophilic Esophagitis (EoE).
Interventions
DIAGNOSTIC_TESTSurface Electromyography
Tests performed to evaluate swallowing function
DIAGNOSTIC_TESTFiberoptic Endoscopic Evaluation of Swallowing
Assessment of swallowing function
Sponsors
Mayo Clinic
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Controls * Normal video swallow or score of 0 for dysphagia on ESSAI questionnaire * absence of dysphagia * age \>18 EoE participants * Documentation of EoE diagnosis by histologic criteria, * \>15 eos/hpf on most recent esophageal biopsy * age \>18
Exclusion criteria
* Abnormal baseline video swallow * lack of MSK coordination to eat test meal * underlying neuromuscular disorder.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Preparatory phase time | Through study completion an average of 2 days | Comparison of preparatory phase between cohorts |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Time difference in swallow initiation | Through study completion an average of 2 days | Time difference in swallow initiation between fiberoptic endoscopic evaluation of swallowing (FEES) vs sEMG |
Countries
United States
Contacts
Primary ContactRyan Alexander, MD
Backup ContactMariah Robran, CCRP
Outcome results
None listed