Heart Failure
Conditions
Brief summary
Acute decompensated heart failure (ADHF) is a severe condition characterized by rapid deterioration of cardiac function, leading to impaired oxygen delivery and multi-organ dysfunction. ADHF often results in reduced physical and respiratory capacity, greater dependence on oxygen support, difficulty performing daily activities, and prolonged hospital stays. In recent years, early exercise-based cardiopulmonary rehabilitation (CPR) has been introduced as part of heart failure management. Evidence suggests that early CPR improves overall health and cardiac function in heart failure patients. However, data regarding its effects in ADHF remain limited. While some studies indicate that early CPR enhances physical function, its impact on respiratory parameters and clinical outcomes is less well established. Cardiopulmonary rehabilitation is a multidisciplinary program designed to promote physical, psychological, and social recovery in patients with cardiovascular and pulmonary diseases. It includes exercise training, education, psychosocial support, and behavioral strategies. Early CPR specifically aims to improve cardiovascular and respiratory functions in heart failure patients. Initiating CPR in the early phase of ADHF may accelerate recovery, strengthen cardiopulmonary function, shorten hospitalization, and improve quality of life. This study aims to evaluate the effects of early CPR on functional capacity, hemodynamic parameters, and respiratory parameters in patients with ADHF.
Interventions
OTHEREarly Cardiopulmonary Rehabilitation
An individualized CPR program including positioning, deep breathing exercises (diaphragmatic and segmental breathing exercises), pursed-lip breathing exercises, breathing exercises using incentive spirometry, and progressive mobilization exercises (in-bed range of motion exercises, sitting, standing, and walking exercises)
OTHERRoutine in-hospital care
Routine in-hospital care for acute decompansated heart failure
Sponsors
Izmir Bakircay University
Istanbul University - Cerrahpasa
Saglik Bilimleri Universitesi
Yeditepe University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Patients hospitalized with a diagnosis of acute decompensated heart failure * Being clinically stable
Exclusion criteria
* Having diagnosed pulmonary, neurological, renal, liver, gastrointestinal, orthopedic or oncological pathologies * Having cardiomyopathy or congestive pericarditis * Recent heart surgery in the past 6 months * New or suspected thromboembolic event * Presence of open wounds, ulcerations or major dermatological diseases in the lower extremities
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Functional capacity | At baseline and at hospital discharge, up to 14 days after admission | It will be evaluated using 6-min walk test according to the guideline of American Thoracic Society |
| Physical performance | At baseline and at hospital discharge, up to 14 days after admission | It will evaluated using Short Physical Performance Battery. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Maximum inspiratory and expiratory capacity | At baseline and at hospital discharge, up to 14 days after admission | It will be evaluated using incentive spirometer. |
| Hemodynamic responses to exercise | At baseline and at hospital discharge, up to 14 days after admission | The change in heart rate before and after exercise will be recorded |
| Subjective symptom responses to exercise | At baseline and at hospital discharge, up to 14 days after admission | Subjective symptom responses to exercise will be evaluated by determining changes in the Modified Borg Dyspnea and Fatigue scales before and after exercise. |
Countries
Turkey (Türkiye)
Outcome results
None listed