Malocclusion, Angle Class I
Conditions
Brief summary
This single-blinded, split-mouth randomized controlled trial investigates whether micro-osteoperforations (MOPs) can accelerate maxillary canine retraction in orthodontic patients requiring bilateral premolar extraction. The study also evaluates postoperative pain levels using the Visual Analog Scale at 1, 3, and 7 days.
Detailed description
MOPs are a flapless, minimally invasive surgical technique that stimulates bone remodeling and may reduce orthodontic treatment time. In this trial, one side of each patient receives MOPs while the contralateral side serves as control. Canine retraction is performed using miniscrews, power arms, and NiTi coil springs. Outcomes include the rate of canine movement over 16 weeks and pain assessment using VAS.
Interventions
PROCEDUREMicro-osteoperforations (MOPs)
Maxillary canine retraction with miniscrew anchorage and NiTi closed-coil springs, without micro-osteoperforations.
PROCEDUREConventional Canine Retraction
Maxillary canine retraction with miniscrew anchorage and NiTi closed-coil springs, without micro-osteoperforations
Sponsors
Can Tho University of Medicine and Pharmacy
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Masking description
Only the outcome assessor was blinded to the intervention allocation. Patients and treating clinicians were aware of the intervention side, but the examiner performing digital measurements and statistical analysis did not know which side received MOPs.
Intervention model description
This is a single-blinded, split-mouth randomized controlled trial. Each participant received both interventions: on one side of the maxillary arch, micro-osteoperforations (MOPs) were performed distal to the canine, while the contralateral side served as the control with conventional retraction. Outcomes were measured within the same patient, reducing inter-individual variability.
Eligibility
Sex/Gender
ALL
Age
16 Years to 25 Years
Healthy volunteers
Yes
Inclusion criteria
* Age 16-25 years * Patients requiring bilateral extraction of maxillary first premolars as part of orthodontic treatment * Angle Class I molar relationship * No previous orthodontic treatment
Exclusion criteria
* History of craniofacial trauma or congenital anomalies * Systemic or bone-related diseases * Current smoking * Use of medications affecting bone metabolism
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Rate of Maxillary Canine Retraction | Baseline, 4, 8, 12, and 16 weeks | Distance of maxillary canine retraction measured on 3D digital dental models using intraoral scanning. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Pain Level (VAS Score) | Day 1, Day 3, Day 7 after intervention | atient-reported pain intensity measured using a 10-cm Visual Analog Scale (VAS), with scores ranging from 0 (no pain) to 10 (worst pain imaginable). |
Countries
Vietnam
Outcome results
None listed