COVID-19 Pneumonia, Hepatitis B, Hypoxemia
Conditions
Brief summary
The aim of this observational cohort study was to evaluate adherence to hepatitis B virus (HBV) screening guidelines in a country characterized by low HBV prevalence and assess the potential reactivation and progression of HBV infection in anti-HBV core antigen antibodies (anti-HBc) positive patients receiving corticosteroids for coronavirus disease 2019 (COVID-19).
Interventions
DIAGNOSTIC_TESTHepatitis B virus infection
anti-hepatitis B virus core antigen positive serologic status
Sponsors
University Medical Centre Ljubljana
Study design
Observational model
COHORT
Time perspective
OTHER
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* hospitalized adult patients with a positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ribonucleic acid (RNA) polymerase chain reaction (PCR) test * supplemental oxygen * treated with corticosteroids for COVID-19 pneumonia
Exclusion criteria
* age under 18 years * hospitalized for medical conditions unrelated to COVID-19 * received corticosteroid therapy for non-COVID-19 reasons
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| HBV reactivation | at least 3 months post treatment with corticosteroids | number (%) of patients with HBV reactivation |
| number (%) of patients with HBV reactivation | one year | — |
Countries
Slovenia
Outcome results
None listed