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Efficacy of Combining Movement Representation Techniques to Active Neural Mobilization in the Mechanosensitivity of the Median Nerve in Asymptomatic Volunteers.

Efficacy of Combining Movement Representation Techniques to Active Neural Mobilization in the Mechanosensitivity of the Median Nerve: A Pilot Study, Single-blind,Randomized, Crossover.

Status
Not yet recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07154017
Enrollment
10
Registered
2025-09-04
Start date
2025-09-30
Completion date
2025-12-31
Last updated
2025-09-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Median Nerve

Keywords

Movement Representation Techniques, Neural Mobilization, Mechanosensitivity

Brief summary

The objective of this study will be to determine whether the combination of movement imaging techniques with neural mobilization (NM) exercises works to modify median nerve sensitivity to mechanical stimuli. Movement Representation Techniques (MRTs) are defined as therapeutic or training systems that neurophysiologically evoke a perceptual-cognitive representation of movement. They can be combined with the execution of actual movement or with afferent sensory stimulation (motor command). There is evidence demonstrating positive results in pain reduction and improved range of motion using MRTs alone. The study will be evaluated in 10 randomly selected asymptomatic volunteers, considering the following variables: pressure pain threshold, elbow extensor range of motion, and sensory responses before and after the intervention, in both the experimental and control groups. The period between interventions will be 72 hours.

Detailed description

The objective of this pilot study will be to determine the efficacy of combining movement representation techniques with neural mobilization (NM) exercises on median nerve mechanosensitivity. Movement representation techniques (MRTs) are defined as therapeutic or training systems that neurophysiologically evoke a perceptual-cognitive representation of movement through imagery or observation of motor actions. They can be combined with actual movement execution or with afferent sensory stimulation (motor command). There is evidence demonstrating positive results in pain reduction and range of motion gains using MRTs alone. The study will be designed as a randomized, single-blind, crossover pilot clinical trial. In this study, 10 asymptomatic volunteers will be randomly selected and measured in the following variables: pressure pain threshold (PPT), elbow extensor range of motion (EROM), and the spatiotemporal distribution of pre- and post-intervention sensory responses in both the experimental group (RMM + MN) and the control group (MN). The washout period between interventions will be 72 hours.

Interventions

OTHERCombination of Movement Representation Techniques with neural mobilization exercises

The experimental intervention will be an exposition of movement representation techniques in an established sequential order, consisting of action observation, implicit/explicit motor imagery and visual feedback with a mirror in combination with neural mobilization exercises.

OTHERNeural mobilization exercises

The control intervention will consist in three series of active neural mobilization exercises

Sponsors

University of Gran Rosario
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
OTHER
Masking
DOUBLE (Investigator, Outcomes Assessor)

Masking description

Evaluators

Intervention model description

A Pilot Study, Single-blind,Randomized, Crossover.

Eligibility

Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
Yes

Inclusion criteria

* asymptomatic volunteers of both sexes * aged 18 to 45 * with no symptoms or history of disease in the cervical region, shoulder girdle, or upper limb.

Exclusion criteria

* history of surgery or trauma to the cervical spine, shoulder girdle, or upper limb; * nonspecific shoulder pain; * presenting symptoms of chronic pain in any region of the body; * aphantasia (inability to create mental images); * hypermobility; * history of cancer or active disease; * current infection; * rheumatological disease; * neurological and/or psychiatric disorders; * altered sensation; * current pregnancy; * consumption of centrally acting medications; * undergoing physiotherapy treatment in the last month; * inability to understand the informed consent document; * previous experience with median nerve provocation testing.

Design outcomes

Primary

MeasureTime frameDescription
Elbow Extensor Range of MotionPre- and post-interventions with a 72-hour washout period, for both control and experimental.The elbow extension movement will be measured during the median nerve provocation test, through digital inclinometry of both the dominant and non-dominant arm by an experienced Physiotherapist.
Pressure Pain ThresholdPre and post interventions, both control and experimentalPre- and post-interventions with a 72-hour washout period, for both control and experimental.Pressure pain thresholds (PPTs) will be performed at two sites, the dominant and non-dominant side, in asymptomatic participants: 1) the upper trapezius muscle, and 2) the proximal third of the forearm. A pressure algometer will be used. The device has a rod at one end with a 1 cm2 flat, circular rubber tip. Pressure will be applied progressively in a perpendicular direction at a rate of 0.5 kgf/cm2 per second to the assessment sites. Volunteers will be asked to verbally report the moment they feel the pressure exerted with the pressure algometer begin to change to a sensation of pain (first painful sensation). At that moment, the evaluator will stop applying pressure and a value will be obtained. Three measurements will be taken at each site, 30 seconds apart. The PPT will be determined as the arithmetic mean of the three measurements.
Spatiotemporal distribution of sensory responsesPre- and post-interventions with a 72-hour washout period, for both control and experimental.Humanoid software (University Center of Assistance, Teaching and Investigation, CUADI, Argentina) will be used to evaluate the spatiotemporal distribution of pain intensity and/or perceived sensations. To mark the sensations that subject feel during the arm stretch test. To do this, the subjects will mark the area on the touchscreen where they perceive tension or stretching. The sensations will be representated by different colours: yellow is used for mild sensations, orange for moderate sensations, and red for intense sensations.

Countries

Argentina

Contacts

Primary ContactMaximiliano Venosta, Physiotherapist
mvenosta@ugr.edu.ar+5493412114064
Backup ContactMauro S Barone, Doctor-Physiotherapist
mbarone@ugr.edu.ar+5493412123037

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026