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An Open Label 100 Person Study Evaluating a Natural Supplement for Weight Loss and Fat Loss.

An Open Label 100 Person Study Evaluating a Natural Supplement for Weight Loss and Fat Loss in a Real World Setting.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07152470
Enrollment
100
Registered
2025-09-03
Start date
2025-01-26
Completion date
2025-12-26
Last updated
2025-09-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Overweight and Obesity

Brief summary

The goal of this clinical trial is to learn if motus, a natural supplement can support healthy weight loss and fat loss in a real world setting without caloric restrictions or exercise requirements. The main questions it aims to answer are: Can a daily dose of motus result in statistically significant weight loss over 3 month and 6 month time points. Participants will: Weigh-in at baseline and every week thereafter Take drug motus every day Complete a food tracker app for every meal and drink product consumed daily Complete an exercise tracker for any activities performed daily Complete weekly satisfaction surveys on various topics

Detailed description

A prospective, observational human study was conducted with 100 participants (ages 25-68, BMI ≥25) over an initial 12-week period, followed by a 12-week extension phase for 40 continuing participants. All subjects received motus (4-capsule daily dose) and were instructed to track food intake and exercise via food tracker app and digital fat measurement scales. No caloric restriction was mandated, and participants could optionally receive nutritional counseling. Weekly weigh-ins and quality of life surveys were completed. No financial compensation was provided. Participants were stratified post hoc into three behavioral groups based on food and activity logs reviewed by registered dietitians: Category 1 (healthy diet + exercise 4+ times per week), Category 2 (average diet + exercise 2-3 times per week), Category 3 (average diet + no exercise) and Category 4 (poor diet + no exercise).

Interventions

BEHAVIORALDiet and Exercise Tracking

To determine if diet and/or exercise had any impact on weight loss while taking motus.

Sponsors

Prostasis, LLC, dba Tonum Health
Lead SponsorINDUSTRY

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 75 Years

Inclusion criteria

* BMI \>25 * Willing to complete daily diary and weekly weigh-ins * Willing to take motus daily

Exclusion criteria

* BMI\<25 * Unwilling to complete daily diary and weekly weigh-ins * Currently taking a prescribed weight loss medication * Currently or planning to be pregnant

Design outcomes

Primary

MeasureTime frameDescription
Total Weight Loss26 weeksTotal weight loss as a percentage of total body weight
Body Fat Loss26 weeksTotal body fat loss compared to lean mass loss

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026