Overweight and Obesity
Conditions
Brief summary
The goal of this clinical trial is to learn if motus, a natural supplement can support healthy weight loss and fat loss in a real world setting without caloric restrictions or exercise requirements. The main questions it aims to answer are: Can a daily dose of motus result in statistically significant weight loss over 3 month and 6 month time points. Participants will: Weigh-in at baseline and every week thereafter Take drug motus every day Complete a food tracker app for every meal and drink product consumed daily Complete an exercise tracker for any activities performed daily Complete weekly satisfaction surveys on various topics
Detailed description
A prospective, observational human study was conducted with 100 participants (ages 25-68, BMI ≥25) over an initial 12-week period, followed by a 12-week extension phase for 40 continuing participants. All subjects received motus (4-capsule daily dose) and were instructed to track food intake and exercise via food tracker app and digital fat measurement scales. No caloric restriction was mandated, and participants could optionally receive nutritional counseling. Weekly weigh-ins and quality of life surveys were completed. No financial compensation was provided. Participants were stratified post hoc into three behavioral groups based on food and activity logs reviewed by registered dietitians: Category 1 (healthy diet + exercise 4+ times per week), Category 2 (average diet + exercise 2-3 times per week), Category 3 (average diet + no exercise) and Category 4 (poor diet + no exercise).
Interventions
To determine if diet and/or exercise had any impact on weight loss while taking motus.
Sponsors
Study design
Eligibility
Inclusion criteria
* BMI \>25 * Willing to complete daily diary and weekly weigh-ins * Willing to take motus daily
Exclusion criteria
* BMI\<25 * Unwilling to complete daily diary and weekly weigh-ins * Currently taking a prescribed weight loss medication * Currently or planning to be pregnant
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Total Weight Loss | 26 weeks | Total weight loss as a percentage of total body weight |
| Body Fat Loss | 26 weeks | Total body fat loss compared to lean mass loss |
Countries
United States