Surgery Benefits Takayasu Arteritis With Stenosis in the Descending Aorta

Surgery Improves Survival Rate in Patients With Takayasu Arteritis: a Retrospective Observational Study

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07149805

Enrollment

Registered

2025-09-02

Start date

2004-01-01

Completion date

2025-01-01

Last updated

2025-09-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Takayasu Arteritis

Brief summary

The long-term prognosis and optimal management for Takayasu arteritis(TA) patients with severe stenosis of the descending thoracic and abdominal aorta remain undefined. We want to compare the clinical outcomes of surgical intervention and medical management.

Interventions

PROCEDUREopen surgery or interventional treatment

open surgery or interventional treatment

Study design

Observational model

CASE_CONTROL

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

1. fulfilling the 1990 American College of Rheumatology criteria for the diagnosis of TA; 2. having at least one site with severe narrowing in the descending thoracic and abdominal aorta; 3. having symptoms caused by TA-related stenosis, such as uncontrolled hypertension, heart failure, renal ischemia, dizziness, visual disturbances, and claudication

Exclusion criteria

Patients with arterial stenosis due to other reasons (such as typical atherosclerosis, congenital coarctation of the aorta, and anatomical abnormality) were excluded

Design outcomes

Primary

Measure	Time frame
all-cause mortality rate	Patients underwent follow-up from discharge until study termination (3 years to 11 years) or death, whichever came first

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026