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Comparison of Cervical Extensor Muscle Thickness, Fat Infiltration, and Cervical Alignment in Patients With Ankylosing Spondylitis With a Healthy Population: a Retrospective Controlled Study

Cervical MRI Findings in Patients With Ankylosing Spondylitis

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07148167
Enrollment
158
Registered
2025-08-29
Start date
2025-01-01
Completion date
2025-11-30
Last updated
2026-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Muscle Planes, Muscle Volumes, Fat Infiltration in Cervical MRI

Brief summary

In the literature, we found only one study evaluating the thickness of the cervical paraspinal muscles (multifidus, semispinalis cervicis, semispinalis capitis, splenius capitis, and trapezius) in patients with AS. This study examined the morphology of all neck extensor muscles (multifidus, semispinalis capitis, semispinalis cervicis, splenius capitis, and trapezius muscles) using ultrasound and their relationship to activities of daily living and compared them with a control group. As is well known, the user's experience is crucial in ultrasound. Furthermore, ultrasound cannot accurately assess the deep paravertebral muscles. Therefore, inspired by this study, we decided to use Magnetic Resonance Imaging (MRI) to evaluate the cervical muscle planes in AS patients in more detailed and objective ways. In this study, in addition to cervical muscle volumes in AS patients, we also aimed to evaluate cervical fat infiltration and cervical alignment, which have not been previously evaluated in AS patients.

Interventions

OTHERMagnetic resonance imaging

use Magnetic Resonance Imaging (MRI) to evaluate the cervical muscle planes in AS patients in more detailed and objective ways. In this study, in addition to cervical muscle volumes in AS patients, we also aimed to evaluate cervical fat infiltration and cervical alignment, which have not been previously evaluated in AS patients.

Sponsors

Kayseri City Hospital
Lead SponsorOTHER_GOV

Study design

Observational model
CASE_CONTROL
Time perspective
OTHER

Eligibility

Sex/Gender
ALL
Age
18 Years to 50 Years
Healthy volunteers
Yes

Inclusion criteria

* For the study group: * Patients diagnosed with ankylosing spondylitis, aged 18-50. * Patients who underwent a cervical MRI between January 2020 and September 2023. Control Group Patients aged 18-50 who underwent cervical MRI between January 2020 and September 2023 due to nonspecific neck pain, who did not have an AS diagnosis and whose cervical MRI was reported as normal.

Exclusion criteria

* Patients over 50 years of age * History of spine surgery; * Presence of pain, numbness, and weakness in the upper extremities * History of cervical injury or neck injury * Presence of tuberculosis, tumor, fracture, infection, instability, cervical myelopathy, cervical disc herniation (protrusion, extrusion) (will be considered cervical bulging) * Presence of cervical radiculopathy * Those with a detectable pathological spinal condition related to neck pain, including spinal deformity; inflammatory or rheumatic diseases other than AS, malignancies, or neurological diseases * A cognitive or psychological disorder

Design outcomes

Primary

MeasureTime frameDescription
servical MRI fındings in AS patients,Patients who underwent cervical MRI between January 2020 and September 2023the cervical muscle planes, cervical muscle volumes in AS patients cervical fat infiltration

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 21, 2026