Chronic Obstructive Pulmonary Disease (COPD), Sedation and Analgesia
Conditions
Keywords
Choronic Obstructive Pulmonary disease (COPD), sedation and analgesia
Brief summary
this study is to compare no-sedation versus daily interruption of sedation (DIS) in Chronic obstructive pulmonary disease (COPD) patients receiving mechanical ventilation upon the ventilator-free days.
Interventions
BEHAVIORALdaily Interruption of Sedation
The patients will be managed by DIS. Richmond agitation and sedation score (RASS) will be used for monitoring the depth of sedation
Sponsors
Benha University
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients of both sex aged 18 years or older * The study will include 60 patients divided into 2 equal groups * Invasive mechanical ventilation * Patients with COPD patients (post-bronchodilator FEV1/FVC\< 70, and under follow through the department outpatient clinic) exacerbation admitted to the ICU and required invasive mechanical ventilation were recruited.
Exclusion criteria
Allergy to sedative which will be used * renal or hepatic impairment * proven or suspected psychiatric or neurological impairment * pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Ventilator-free days | from day-1 to day-28) | Ventilator-free days (Number of days from day-1 to day-28) on which the patient did not need assistance to his breathe. |
Countries
Egypt
Outcome results
None listed