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The Impact of Ischemic Preconditioning on Exercise Performance and Physiological Function

Ischemic Preconditioning Enhances Autonomic Nervous System Modulation During Frequency Speed of Kick Test in Taekwondo Athletes: A Randomized Crossover Study

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07146399
Enrollment
15
Registered
2025-08-28
Start date
2023-12-31
Completion date
2024-02-07
Last updated
2025-08-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Autonomic Nervous System (ANS) Functioning and Mood State, Ischemic Preconditioning

Keywords

Ischemic preconditioning, Autonomic nervous system, Heart rate variability, Heart rate recovery

Brief summary

Ischemic Preconditioning has been confirmed to prevent long-term ischemic damage to tissues, among which the improvement of autonomic nerve system function may be one of its mechanisms of action. In recent years, IPC has gradually been applied to enhance athletic performance and accelerate postexercise recovery; however, there has been limited research on the effects of IPC on ANS function and competitive condition before and after exercise. This study investigated the effects of IPC on ANS function before and after sport-specific testing in taekwondo athletes. The objectives of our study are (1) to investigate the impact of IPC on two indicators of autonomic nervous function-HRV and HRR-and (2) to reveal the coordinating effect of IPC on the sympathetic and parasympathetic nervous systems during the warm-up phase and after specific testing in taekwondo athletes. The investigators hypothesize that IPC enhances sympathetic drive during the warm-up phase and rapidly activates the parasympathetic nervous system postexercise, which is accompanied by improvements in the athletes' competitive condition.

Interventions

PROCEDUREIschemic Preconditioning

Compression cuff width: 10CM; Compression duration: 5min/5min (ischemia/reperfusion) \*4. 220 mmHg

PROCEDURESham (No Treatment)

Compression cuff width: 10CM; Compression duration: 5min/5min (compression/relaxation) \*4. 20 mmHg

Sponsors

Guangzhou Sport University
CollaboratorOTHER
Ziyue Ou
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
OTHER
Masking
DOUBLE (Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
MALE
Age
18 Years to 22 Years
Healthy volunteers
Yes

Inclusion criteria

* Taekwondo athletes with a national ranking of level two or higher, including those placed in the top three at the Provincial Professional Taekwondo Championship (combat) and the top eight at the National Professional Taekwondo Championship (combat); * adult males aged 18 years or older; * regular participation in specialized Taekwondo training for the past three months. * All the subjects were from the same team.

Exclusion criteria

* consumption of alcohol or caffeine within 24 hours prior to the experiment; * engagement in strenuous physical activity within 24 hours before the experiment; * presence of acute or chronic diseases, including cardiovascular diseases, anxiety disorders, and metabolic diseases; * use of creatine supplements

Design outcomes

Primary

MeasureTime frameDescription
Taekwondo-specific sports performance test.Five minutes after the intervention, a standard warm-up lasting 10 minutes is conducted. Following the warm-up, a rest period of 5 minutes is observed. Subsequently, three sets of specialized sports performance tests are administered, with each set lastiThe specialized athletic ability in Taekwondo is measured by the number of kicks performed during the test.
Heart rate variabilityThe measurement time points were as follows: heart rate variability was assessed in the resting state upon participants' arrival at the testing site, after a warm-up, and following the sport-specific performance test.Used to measure the autonomic nervous function of taekwondo athletes.
Heart rate recoveryThe measurement time points were established as follows: heart rate recovery was assessed for 1 minute during the intervals of each test group. Additionally, heart rate recovery was recorded at both 1 minute and 5 minutes following the completion of threUsed to measure the autonomic nervous function of taekwondo athletes.
Blood lactateBlood lactate measurements were taken at several key time points during the study: upon participants' arrival at the test site while they were in a quiet state; at the 3rd minute following the conclusion of the intervention; prior to the commencement ofUsed to measure the intensity and metabolic adaptations during the testing process of taekwondo athletes.

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026