Chronic Pain
Conditions
Brief summary
The goal of this observational study is to learn about the analgesia nociceptive index (ANI) is associated with pain sensitivity in patients between the ages of 9-17 who are experiencing chronic pain. The main question it aims to answer is: \- Does the ANI score correlate with the change in the pain sensitivity in patients aged 9-17 undergoing an interventional block. Patients already receiving an interventional block as part of their regular medical care for chronic pain will have their level of pain recorded during clinic appointments
Interventions
PROCEDUREInterventional Block
For patients who are offered interventional blocks as part of their standard of care, we will measure ANI as well as pressure pain threshold before, during, and after the block as well and at follow-up to assess correlation with treatment efficacy.
Sponsors
McGill University Health Centre/Research Institute of the McGill University Health Centre
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
9 Years to 17 Years
Healthy volunteers
No
Inclusion criteria
* Experiencing chronic pain defined by: persistent or recurrent pain at least once a week for at least three months in their electronic medical charts or by reference of the patient's physician
Exclusion criteria
* Taking medications known to affect the sympathetic or parasympathetic nervous systems such as cholinomimetics (e.g., pilocarpine), anticholinergics (e.g., ipratropium), sympathomimetics (e.g., salbutamol), and adrenergic antagonists (e.g., propranolol). * Diagnosed cardiac or neurological conditions, including patients with arrhythmias, heart block, postural orthostatic tachycardia syndrome, Guillain-Barre syndrome, or spinal cord injury. * Active cancer diagnosis * Conditions that may interfere with the ability to understand instructions or complete assessments including: cognitive, or developmental delay. * Patients who do not speak English or French.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Validation of analgesia nociception index (ANI) as a tool to assess change in the pain pressure threshold (PTT), measured by the PPT test, of children with chronic pain conditions. | 6 weeks |
Countries
Canada
Contacts
Primary ContactSabrina Carrie, MD
Outcome results
None listed