AMD - Age-Related Macular Degeneration
Conditions
Brief summary
The goal of this observational study is to compare swept source optical coherence tomography devices ability to detect macular neovascularisation when there is a large pigment epithelium detachment higher than 250 microns
Interventions
DIAGNOSTIC_TESTOptical Coherence Tomography Angiography (OCT-A)
Two Optical Coherence Tomography Angiography swept source devices are compared for the detection of large pigment epithelium detachments in age related macular degeneration. The sensitivity of the devices is compared in both the automatic segmentation done by the device and the manual segmentation done by a retina specialist.
Sponsors
University of Trieste
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Patients treated for neovascular age related macular degeneration (AMD) * Presence of a pigmentary epithelium detachment higher than 250 microns measured on structural optical coherence tomography (OCT)
Exclusion criteria
* Poor image quality or signal strength * Undefined retina layers
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Sensitivity of the detection of neovascularisation in large pigment epithelium detachment by swept source optical coherence tomography devices | Day 1 | The optical coherence tomography angiography devices are known to have a difficult time detecting neovascularisation in the cases of large pigment epithelium detachments (PED), because of the many layers and the distance the OCT signal has to cross. The automatic retina segmentation (done by the device of the different retina layers plays a big role in this detection. It's also disturbed by the height of the PED. This study aims to compare the sensitivity of two swept source OCT devices available in the market : Bmizar, Towardpi and Plexelite, Zeiss. After the exam image acquisition, a retina specialist will try to make a manual segmentation of the retina analysed to help the detection of macular neovascularisation that would have been missed in the normal automatic segmentation done by the device. |
Countries
France
Contacts
Primary ContactKamal El Majdoubi El Idrissi, MD
Outcome results
None listed