Bleeding on Probing, Plaque Control, Pocket Depth, Saliva Microbiome
Conditions
Keywords
fermented lingonberry juice, saliva test, mouthrinse, aMMP-8 test
Brief summary
A human intervention study was performed to examine the antimicrobial effects of fermented lingonberry spray (FLJ spray) treatment, used for a period of 30 days.
Detailed description
Traditional clinical oral examinations, periodontal status and sample gatherings were performed at start point, two and four weeks. Bleeding on probing (BOP), visible plaque index (VPI), probing pocket depths (PPD) were examined and active-matrix metalloproteinase - 8 (aMMP-8) mouthrinse assays (Cutt-off 20 ng/ml) were carried out. Additionally, stimulated and resting saliva, pH and buffering capacity were tested as saliva test. A questionnaire assessing dry mouth symptoms was also recorded from the patients.
Interventions
OTHERFermented lingonberry juice sprey
Patented fermented lingonberry juice sprey
Sponsors
University of Helsinki
Lahanna oy
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Healthy patients or patients with systemic diseases with good cognitive abilities * with or without xerostomia.
Exclusion criteria
* use of other mouthwash products, including chlorhexidine * current use of antibiotics.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The effects of fermented lingonberry spray in the mouth. | Up to one month | Changes of bleeding on probing (BOP), from six measurement point, visible plaque index (VPI), score 1-3, probing pocket depths (PPD) and active-matrix metalloproteinase - 8 (aMMP-8) mouthrinse assays (Cutt-off 20 ng/ml), numerical value were carried out to one month. |
| the time points on the levels of each salivary parameter were determined with the repeated measures ANOVA analysis. | 6 weeks | — |
Countries
Finland
Outcome results
None listed