A Comparative Study Between Three Surgical Techniques in Large Angle Exotropia

A Comparative Study Between Three Surgical Techniques in Large Angle Exotropia: Bilateral Lateral Rectus Recession With Medial Rectus Resection, Bilateral Medial Rectus Resection and Resection-Transplantation

Status

Not yet recruiting

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07143032

Enrollment

Registered

2025-08-27

Start date

2025-09-30

Completion date

2027-09-30

Last updated

2025-08-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Exotropia Equal or More Than 50 Prism Diopter

Keywords

exotropia, Recession, Resection, Transplantation

Brief summary

This is a randomized comparative interventional study that aims to compare the surgical outcomes of correcting large angle exotropia (≥50 prism diopter) by three different surgical techniques including: 1/ bilateral lateral rectus muscle recession with unilateral medial rectus muscle resection 2/bilateral medial rectus muscle resection, 3/unilateral medial rectus muscle resection with lateral rectus muscle transplantation,

Detailed description

This is a randomized comparative interventional study that will be conducted on patients with large angle exotropia before and after doing surgical correction using three different surgical techniques including : 1/ bilateral lateral rectus muscle recession with unilateral medial rectus muscle resection 2/bilateral medial rectus muscle resection, 3/unilateral medial rectus muscle resection with lateral rectus muscle transplantation ,to compare the surgical outcomes between them.

Interventions

PROCEDUREExtropia squint surgery

patients with large angle exotropia will be treated by three different surgical techniques including: 1/ bilateral lateral rectus muscle recession with unilateral medial rectus muscle resection 2/bilateral medial rectus muscle resection, 3/unilateral medial rectus muscle resection with lateral rectus muscle transplantation ,to compare the surgical outcomes between them.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

3 Years to 50 Years

Healthy volunteers

Inclusion criteria

* Patients with large-angle exotropia (≥50 prism diopter).

Exclusion criteria

1. Patients with an exodeviation angle of less than 50 prism diopter. 2. History of previous strabismus surgery. 3. Restrictive or paretic strabismus or history of botulinum toxin injections for strabismus.

Design outcomes

Primary

Measure	Time frame	Description
changes in ocular alignment	at one month, 6 month and one year postoperatively.	Detect ocular alignment by using Krimsky test to measure angle of deviation in prism diopter

Contacts

Primary Contactsara ahmed abdelraheem, Assistant lecturer

sara011096@med.sohag.edu.eg+201153987387

Backup ContactAlahmady Hamad Alsaman, Professor

+201111102698

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026