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Investigation of the Effect of Hyperbaric Oxygen Therapy in Patients With Avascular Necrosis

Investigation of the Effect of Hyperbaric Oxygen Therapy on Physical Capacity, Depressive Symptoms, and Quality of Life in Patients With Avascular Necrosis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07142018
Enrollment
20
Registered
2025-08-26
Start date
2025-08-19
Completion date
2025-08-27
Last updated
2025-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Avascular Necrosis of Femur Head

Brief summary

Avascular necrosis is a condition that occurs when bone tissue loses sufficient blood flow. This condition causes bone cells to die and, as a result, bone structure to deteriorate. Hyperbaric oxygen therapy is a treatment method used in patients with avascular necrosis. Avascular necrosis can significantly affect the quality of life of patients. The aim of this study was to investigate the effects of hyperbaric oxygen therapy on physical capacity, depressive symptoms, and quality of life in patients diagnosed with avascular necrosis.

Detailed description

Avascular necrosis is a condition that occurs when bone tissue loses sufficient blood flow. This condition causes bone cells to die and, as a result, bone structure to deteriorate. It is commonly seen in joints such as the hip, knee, ankle, and shoulder. Hyperbaric oxygen therapy is a treatment method used in patients with avascular necrosis. In hyperbaric oxygen therapy, patients breathe 100% oxygen under high pressure. This treatment can help treat avascular necrosis by increasing oxygen, promoting new blood vessel formation, reducing inflammation, and facilitating cell repair mechanisms. Avascular necrosis can significantly affect the quality of life of patients. The effects of avascular necrosis on quality of life can be summarized as follows: Avascular necrosis often causes severe pain and limited mobility in the joint areas. These physical symptoms can prevent patients from performing their daily activities, leading to social isolation and a decline in overall quality of life. The aim of this study was to investigate the effects of hyperbaric oxygen therapy on physical capacity, depressive symptoms, and quality of life in patients diagnosed with avascular necrosis.

Interventions

None listed

Sponsors

Dr. Lutfi Kirdar Kartal Training and Research Hospital
Lead SponsorOTHER_GOV

Study design

Observational model
COHORT
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* Be over 18 years of age, * Receive hyperbaric treatment, * Be diagnosed with avascular necrosis, * Have stage 1-2 avascular necrosis according to the Ficat classification, * Be able to understand and speak Turkish, * Be able to read and write,

Exclusion criteria

* Having undergone orthopedic surgery on the lower extremities, * Having cardio-respiratory failure that prevents walking, * Having a disorder related to the musculoskeletal system other than AVN * Having a diagnosis of avascular necrosis classified as stage 3-4 according to the Ficat classification * Presence of varicose veins, * Presence of urinary stress incontinence, * Presence of systemic or rheumatological disease, * Pregnancy, * Refusal to participate in the study.

Design outcomes

Primary

MeasureTime frameDescription
Beck Depression Inventory1 weekIt is a 21-item, self-report rating inventory that measures characteristic attitudes and symptoms of depression.
Short form 361 weekSF-36 is a set of generic, coherent, and easily administered quality-of-life measures. These measures rely upon patient self-reporting and have been widely used.
tinetti performance oriented mobility assessment measure1 weekThe Tinetti assessment tool is an easily administered task-oriented test that measures an older adult's gait and balance abilities. Scoring: A three-point ordinal scale, ranging from 0-2. 0 indicates the highest level of impairment and 2 the individuals independence.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026