Fertility Perservation, Satisfaction Survey
Conditions
Keywords
fertility preservation, boys, gonadotoxic treatment, male infertility, testicular tissue biopsy, spermatogonial stem cell, cryopreservation, long-term follow-up, survey
Brief summary
Chemotherapy and radiotherapy can lead to spermatogonial stem cell depletion in pre- and peripubertal boys, potentially resulting in infertility during adulthood A testicular biopsy is considered a safe procedure performed in children prior to gonadotoxic treatment as part of a fertility preservation strategy. At the time of the procedure, parental involvement is essential-both in their role as legal guardians and due to the limited cognitive capacity of young boys to fully comprehend fertility preservation counseling. Long-term follow-up is necessary to evaluate the impact on fertility outcomes, psychological well-being, and overall satisfaction. The aim of this survey is to assess the perceived impact of fertility preservation counseling and the physical and emotional effects of undergoing testicular biopsy in this population, with the goal of identifying opportunities to improve patient experience and clinical care for future patients.
Interventions
OTHERSurvey using a questionnaire.
A monocentric experimental study conducted as a survey, including patients enrolled in our fertility preservation program between May 2005 and May 2020. Participants were asked about their current reproductive health status, their experience with the fertility preservation process, and their overall satisfaction with the care they received.
Sponsors
Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Eligibility
Sex/Gender
MALE
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* All patients who have participated in the fertility preservation program aged 18 years old and above
Exclusion criteria
* Deceased patients. Patients undergoing treatment for disease relapse. Patients suffering from a documented mental disorder.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The impact on quality of life of fertility preservation during childhood or adolescence. | From the start of the program in may 2005 and the last patient enrolled in may 2020 | Assessment will be conducted by means of a confidential survey in \> 18 yo patients who have undergone in their childhood a fertility preservation. The number of patients who are eligible for the follow-up survey (n = 64) within the fertility preservation program of the CUSL is important compared to the overall number of boys who have participated in such a FP programme worldwide (n=1033) in 2023. Recipients' satisfaction level will be evaluated by both general and specific scores. The general satisfaction score is calculated by combining the responses to questions rating specifically recipients' satisfaction on specific items using a 5 elements Likert scale (Very Dissatisfied to Very Satisfied) and responses to closed questions which inquire participants' global satisfaction on specific subjects. |
Countries
Belgium
Outcome results
None listed