Stroke, Rehabilitation, Virtual Reality, Mirror Movement Therapy, Task Performance
Conditions
Brief summary
In the proposed study, the investigators assumed that Virtual Reality-Based Generative Bimanual Cooperative Task-Oriented Therapy (VRMCTOMT) will provide a better treatment effects than traditional virtual reality mirror therapy (VRMT) for the patients with unilateral stroke. The aim of the study is to examine the difference in the treatment effects among the combination of task-oriented training with either VRMCTOMT, or VRMT on the upper extremity function and brain activity of the stroke patients.
Interventions
Motor training targeted to goals that are relevant to the functional needs of the patient
Virtual Reality Mirror Therapy using goggle
OTHERVirtual Reality-Based Generative Bimanual Cooperative Task-Oriented Mirror Therapy
Virtual Reality-Based Generative Bimanual Cooperative Task-Oriented Mirror Therapy using goggle
Sponsors
National Cheng-Kung University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* Clinical diagnosis of stroke with unilateral side involved; * A score of Mini-mental state examination greater than 24 for proving higher mental function * Time of onset \> 6 months before treatment begins; and * Premorbid right-handedness.
Exclusion criteria
* Severe vision impairment; * Major cognitive-perceptual deficit; * Other brain disease.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in the result of Fugl-Meyer assessment (FMA) for motor function of upper extremity test | baseline, 9 weeks and 21 weeks | Each item is rated on a three-point ordinal scale (2 points for the detail being performed completely, 1 point for the detail being performed partially, and 0 for the detail not being performed). The maximum motor performance score is 66 points for the upper extremity. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in the result of Modified Ashworth scale (MAS) | baseline, 9 weeks and 21 weeks | Muscle tone is defined by the resistance of a muscle being stretched without resistance. |
Other
| Measure | Time frame | Description |
|---|---|---|
| Change in the result of Box and blocks test | baseline, 9 weeks and 21 weeks | The score is the number of blocks carried from one box to the other in one minute. Higher values represent a better outcome. |
| Change in the result of Semmes-Weinstein monofilament (SWM) test | baseline, 9 weeks and 21 weeks | The Semmes-Weinstein monofilamenttest examines the cutaneous pressure threshold, range from 1.65-6.65. Higher values represent a worse outcome. |
| Change in the result of Motor Activity Log | baseline, 9 weeks and 21 weeks | Semi-structured interview examine how much and how well the subject uses their more-affected arm for 30 ADLs. Score range from 0-5. Higher values represent a better outcome. |
| functional Magnetic Resonance Imaging | baseline, 9 weeks | a non-invasive neuroimaging technique that measures brain activity by detecting changes in blood oxygenation (BOLD signal). |
Countries
Taiwan
Contacts
Primary ContactHsiu-Yun Hsu, Ph.D
Outcome results
None listed