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Impact of Gender Difference and Exercise Intensities on Depression and Anxiety Symptoms Among University Students

Impact of Gender Difference and Exercise Intensities on Depression and Anxiety Symptoms Among University Students

Status
Not yet recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07139249
Enrollment
84
Registered
2025-08-24
Start date
2025-08-20
Completion date
2026-02-01
Last updated
2025-08-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anxiety, Depression, Exercise Intensity, Gender, University Students

Brief summary

This study was done to investigate the impact of gender differences and exercise intensities on depression and anxiety symptoms among university students

Detailed description

Depression among university students is a growing concern due to factors such as separation from family, transition to a performance-based environment, financial stressors, and uncertainty about postgraduation. An estimated 71% of Egyptian university students have at least minor depression. Depression is associated with lower academic performance and can lead to substance abuse, chronic conditions, and premature mortality. Despite the availability of effective treatment, only one in five university students receives minimally adequate treatment. Physical exercise is suggested as an affordable, low-cost, non-pharmacological treatment for depression and anxiety. Exercise can effectively relieve anxiety symptoms, and a study will evaluate depression and anxiety symptoms based on gender and exercise intensity among university students.

Interventions

OTHERThe high intensity interval training

The training program for students in groups 1 and 2 involves high intensity interval training exercises, conducted three times per week for six weeks. The sessions include a 10-minute warm-up at 40% Heart Rate Reserve, four high-intensity work periods at 85-95% Heart Rate Reserve, three low-intensity work periods at 60-70% Heart Rate Reserve, and a 5- 10 minute cool down at 30% Heart Rate Reserve.

OTHERThe study moderate continuous training

All students in groups 3&4 will receive moderate continuous training 3 times per week for 6 weeks. Each session 40 to 50 minutes included a 5 to 10 minute warm-up, fo followed by 30 minutes of moderate aerobic exercise (treadmill walking exercise) with constant intensity at 60% to 70% Heart Rate Reserve and 5 to 10 minutes cool-down

Sponsors

Cairo University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
18 Years to 25 Years
Healthy volunteers
Yes

Inclusion criteria

* Being a student in higher education * Being single * Age between 18 and 25 years of both sexes * Accepting the principle of randomization in the trial. * The body mass index is 18.5-24.9 kg/m². * Diagnosed by psychiatrist as having a mild to moderate degree of anxiety and depression. * Having scores of 7-24 on the Hamilton Rating Scale for Depression. * Having scores of 17-30 on the Hamilton Anxiety Rating Scale.

Exclusion criteria

* Neurological history such as illness or head trauma * Present severe and unstable respiratory disease * History of heart defect or cardiovascular disease or any other medical conditions prohibiting high-intensity sport or physical activity * Being professional athlete. * Involved in regular routine of exercises * Taking medication for mental health history of any neurological disorders like neuropathy or seizures.

Design outcomes

Primary

MeasureTime frameDescription
assessment of the severity of depressive symptomsat baseline and after 6 weeksThe Hamilton Rating Scale for Depression will be used to assess the severity of depressive symptoms in students across six groups. The 17-item version ranges from 0 to 54, with scores ranging from 0 to 24. Scores between 0 and 6 indicate no depression, while scores between 7 and 17 indicate mild, 18-24 indicate moderate, and 24+ over 24 indicate severe depression. A decrease in scores of at least 50% indicates response, and scores of 7 or less after treatment indicate remission. The 17-item version has adequate reliability and validity.

Secondary

MeasureTime frameDescription
assessment of severity of perceived anxiety symptomsat baseline and after 6 weeksThe Hamilton Rating Scale for Anxiety is a tool used to assess the severity of perceived anxiety symptoms. It consists of 14 symptom-defined elements, scoring from 0 to 4 (severe). The score range is 0 to 56, with scores above 17/56 indicating mild anxiety, 25-30 indicating moderate anxiety, and \>30 indicating severe anxiety. It has good psychometric properties.
assessment of physical fitnessat baseline and after 6 weeksThe Harvard Step Test is a physical fitness index that measures an individual's ability to recover from muscular work and perform muscular tasks. It is performed on a 33 cm bench at 30 steps per minute, with heart rate measured every two seconds. The test is valid for estimating the cardiorespiratory fitness of college students and can be divided into three categories: excellent, good, average, and poor. The physical efficiency index rating ranges from 96 to 115, with the highest rating being excellent for males and the lowest being poor. The test is a reliable tool for assessing physical fitness.
assessment of heart rate during exerciseat baseline and after 6 weeksA pulse oximeter will be used to continuously monitor heart rate during exercise, ensuring the target heart rate (THR) remains within the pre-calculated value. The heart rate will be measured and monitored for all participants using the Karvonen formula. The process involves cleaning the index finger, placing the pulse oximeter on the index, and keeping the pulse for at least a minute until the reading stabilizes.

Countries

Egypt

Contacts

Primary ContactAya Mohamed Hassan Abo Elhassan, Assistant lecturer
aaboelhassan@horus.edu.eg01220042634

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026