EUS- and US- Guided Biopsy for Pancreatic Lesion

Comparison of Safety and Effectiveness Between Endoscopic Ultrasound-guided and Ultrasound-guided Pancreatic Biopsy in Focal Pancreatic Disease: A Multi-center, Retrospective, Propensity Score Analysis

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07138976

Enrollment

2517

Registered

2025-08-24

Start date

2025-08-18

Completion date

2025-12-31

Last updated

2025-08-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pancreatic Cancer

Brief summary

Endoscopic ultrasound (EUS) and ultrasound (US) are the two primary imaging modalities used to guide pancreatic needle biopsy. This study aimed to compare the diagnostic performance and complications associated with EUS- and US-guided pancreatic biopsies.

Interventions

OTHERsampling tissue

EUS- and US- guided pancreatic biopsy

Study design

Observational model

CASE_CONTROL

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 85 Years

Healthy volunteers

Inclusion criteria

* Between January 2017 and December 2023, 2663 consecutive patients with focal pancreatic disease underwent 2729 procedures for pancreatic tissue acquisition from focal pancreatic lesions at seven university teaching hospitals in China.

Exclusion criteria

* Patients were excluded from the study if they had less than 12 months of follow-up, were lost to follow-up, had incomplete follow-up data, or underwent intraoperative biopsy or fluid aspiration.

Design outcomes

Primary

Measure	Time frame
diagnostic inaccuracy	1-year

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026