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Seizure Identification on the Intensive Care Unit (ICU)

Seizure Semiology Identification and Agreement in the Intensive Care Setting: How do Clinical Scientists Compare to Other Healthcare Professionals (Intensivists, Neurologists, ITU Nurses and Neurophysiologists) in Identifying and Interpreting Clinical Signs in Patients on the Adult Intensive Care Unit

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07136298
Enrollment
40
Registered
2025-08-22
Start date
2025-03-03
Completion date
2025-08-31
Last updated
2025-08-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Seizures

Keywords

Intensive Care, Clinical Scientist, Neurologists, Intensivists, ITU Nurses

Brief summary

The aim of this project is to assess the ability of different groups of National Heath Service (NHS) professionals to correctly identify clinical seizures, and distinguish them from other movements commonly seen in the ICU environment, when shown digital video recordings only. Patients on the ICU are at risk of having seizures, however also commonly make other movements, including shivering, jerking, tics and tremors. An Electroencephalogram (EEG) records the brain wave activity and can help distinguish epileptic seizures from other movements. In a study by Bendadis et al (2010), 52 video-EEGs were reviewed containing possible seizures on the ICU. They found only 27% recorded actual epileptic events, with the other 73% having a range of other movements. Malone et al (2009) studied accuracy of diagnosis of 20 video recordings of clinical episodes on the neonatal unit, comparing different staff groups. They found no significant difference between Doctors and Nurses in correctly identifying seizures, however found that accuracy of diagnosis was generally poor. Clinical scientists are currently expanding their roles and responsibilities across Neurophysiology, including giving consultant-level advice on EEG investigations. EEG recordings on the ICU are often obscured by excessive, unavoidable electrical/movement artefacts caused by equipment such ventilators and pumps, and patient factors such as position, breathing artefact and suctioning. These make the EEG difficult to interpret (Boggs 2021). Assessing the clinical signs and symptoms which we may see in ICU patients, in the absence of interpretable EEG, is an essential skill. This study aims to assess Clinical Scientists skills at clinical interpretation, in comparison with other staff groups in the ICU setting. Staff will be asked to watch video clips of events captured in the ICU, and tell us whether they think they are seizures or not, and explain their thought process behind the decision.

Interventions

OTHERClinical Opinion

Staff participants will be asked to review video clips of events captured during EEGs performed on the ICU and asked to state whether they think the event was an epileptic seizure or not, and what aspects of each event led them to that decision

Sponsors

Nottingham University Hospitals NHS Trust
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
Yes

Inclusion criteria

Staff working at Nottingham University Hospitals (NUH) in one of the following staff groups; * Neurophysiology Scientists/Clinical Physiologists at Band 7 level and above, * Neurophysiologists who have completed the CCT in Neurophysiology with at least 1 year of Adult ICU experience. * members of the Neurology medical team with at least 1 years' experience of covering ITU * Intensivists with at least 1 year's experience working on the Adult intensive care unit * Nursing staff working on the Intensive care unit with at least 1 year's experience

Exclusion criteria

* Staff not employed by NUH i.e. agency staff * Staff in other groups not mentioned above

Design outcomes

Primary

MeasureTime frameDescription
Level of Agreementthrough study completion, an average of 1 yearThe primary outcome measure is the level of agreement between the clinical opinion of the different staff groups and the EEG result

Secondary

MeasureTime frameDescription
Interrater Reliabilitythrough study completion, an average of 1 yearThe level of agreement between the different individuals in each staff group.
Thematic Analysisthrough study completion, an average of 1 yearthematic analysis of the decision making process (based on the free text justifications for why individuals made the choice they did)

Countries

United Kingdom

Contacts

Primary ContactJames S Baird
james.baird@nhs.net01159709146

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026