Cranial Nerve Functions in Behçet's Disease and Their Relationship With Clinical Parameters

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07135063

Enrollment

Registered

2025-08-21

Start date

2025-10-31

Completion date

2026-09-30

Last updated

2025-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Behcet Disease, Cranial Nerve Disorder

Brief summary

The goal of this study is to find out whether cranial nerves are affected in people with Behçet's Disease (BD), and how this might relate to other disease features. Cranial nerves control important functions such as vision, facial movement, hearing, swallowing, and balance. The main questions this study will address are: * Do people with BD have changes in cranial nerve function compared to healthy individuals? * Are these changes linked to disease duration, symptoms, or lab results? Participants will: * Answer questions about their medical history and BD symptoms * Complete questionnaires on daily function, mood, and autonomic symptoms * Have a clinical examination of all 12 cranial nerves * Undergo non-invasive electrical tests to assess nerve function This study will not involve any medications. All procedures will be completed in one visit.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 75 Years

Healthy volunteers

Yes

Inclusion criteria

* Aged 18-75 * Diagnosed with BD according to ACR/EULAR 2013 criteria (patient group) * Healthy with no relevant medical history (control group)

Exclusion criteria

* Conditions affecting CN assessment (e.g., facial trauma, surgery, radiotherapy) * Other rheumatologic or autoimmune diseases * Psychiatric disorders, alcohol/substance abuse * Pregnant women * Use of pacemakers or recent botox to masseter muscle

Design outcomes

Primary

Measure	Time frame	Description
Establish the presence or absence of cranial nerve involvement in BD.	Once: Upon patient inclusion	Upon patient inclusion EMG and clinical examination is carried out

Secondary

Measure	Time frame
Investigate relation between disease duration (months) and cranial nerve involvement in BD patients	Once: Upon patient inclusion

Countries

Turkey (Türkiye)

Contacts

Primary ContactReihaneh Houshyar Zarnaghi, Assistant Doctor

h.reihaneh1991@gmail.com+90 536 507 3539

Backup ContactMehmet Tuncay Duruöz, Professor Doctor

prof.tuncayduruoz@gmail.com

Outcome results