Autism
Conditions
Keywords
Virtual Reality, motor training
Brief summary
The goal of this clinical trial is to learn if autism affect motor functions, including muscle strength, balance, and motor control? Additionally, understanding the motor functions, cognitive functions, and brain activation in individuals with autism, and verifying whether motor training can effectively improve muscle strength, balance, and motor control. The main questions aim to answer are: \[primary hypothesis or outcome measure 1\]? \[primary hypothesis or outcome measure 2\]? If there is a comparison group: Researchers will compare \[arm information\] to see if \[insert effects\]. Participants will \[describe the main tasks participants will be asked to do, interventions they'll be given and use bullets if it is more than 2 items\].
Interventions
BEHAVIORALVR-based motor training
Six weeks, twice per week.
Sponsors
National Taiwan University Hospital
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
\> The ASD Group Inclusion criteria: * young adult aged between 18 and 45 years who had a diagnosis of ASD from a licensed mental health or medical professional based on DSM-5. * was motivated to complete the 6-week VR-based motor function training. * had a full-scale IQ \> 70 on the WAIS-IV.
Exclusion criteria
* a history of major mental illness (e.g., bipolar affective disorder, schizophrenia, or psychosis), neurological diseases (e.g., stroke, lumbar radiculopathy, or spinal cord injury) that hamper walking function, or neurosurgery. * visual impairment and/or hearing impairment that would preclude participation in motor assessment or training. * The Non-ASD control group Inclusion criteria: * young adult aged between 18 and 45 years who do not have a diagnosis of ASD. * had a full-scale IQ \> 70 on the WAIS-IV.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The performance of movement operational assessment | 40 minutes | Participants will take movement operational assessment, which composed of different tests, such as Timed Up and Go Test (TUG), the 10-meter walk test (10MWT) and the 6-minute walk test (6WMT) |
| The performance of motor coordination control | 1 hour, twice | the performance recorded with Vicon, an motion capture system, and Single Leg Stance Test |
Secondary
| Measure | Time frame |
|---|---|
| The N-back Task performance | 40 minutes |
| The performance of Timed Up and Go Test (TUG) | 1 minute, twice |
| The performance of the 10-meter walk test (10MWT) | 1 minute, twice |
| The performance of 6-minute walk test (6WMT) | 6 minutes, twice |
Countries
Taiwan
Contacts
Primary ContactYi Ling Chien, Clinical Professor
Outcome results
None listed