Surgery
Conditions
Brief summary
The goal of this study is to use electromyography-based train-of-four monitoring (TetraGraph™ Neuromuscular Transmission Monitor) as a means of evaluating differences in neuromuscular transmission between infants ≤ 3 months of age and adolescent and older patients (≥ 12 years of age).
Interventions
DEVICETetraGraph
TetraGraph is a unique, EMG-based portable device for quantitative (objective) monitoring of neuromuscular function. It is a precise and easy to use tool for monitoring depth of block, ensuring adequate recovery of muscle function, and aiding the clinician to reduce the incidence of residual block.
Sponsors
Joseph D. Tobias
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
28 Days to 25 Years
Healthy volunteers
No
Inclusion criteria
* ASA 1-3 patients * Aged 28 days - 3 months or ≥ 12 years * Undergoing a surgical procedure with a volatile-agent based anesthetic that does not require administration of a neuromuscular blocking agent
Exclusion criteria
* Patients with history of a peripheral neurologic or neuropathic disorder * Patients in whom the upper extremity cannot be used for TOF monitoring * Patients undergoing a surgical procedure in which neuromuscular blockade is required * Edematous patients * Patients receiving total intravenous anesthesia (TIVA)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Amplitude | First 30 minutes of surgery | Average amplitude of the evoked response of the muscles. |
Countries
United States
Contacts
CONTACTJulie Rice-Weimer, RN
CONTACTCatherine Roth, MPH
PRINCIPAL_INVESTIGATORJoseph D Tobias, MD
Nationwide Children's Hospital
Outcome results
None listed