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Randomized Suicide Prevention Trial Using ASSIP and ACT in Suicide Attempters

RCT Comparing ASSIP and ACT on Mental Pain and Suicidal Ideation in Individuals With Suicide Attempts

Status
Recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07132099
Enrollment
60
Registered
2025-08-20
Start date
2025-08-01
Completion date
2025-10-31
Last updated
2025-08-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Suicide, Suicide Ideation

Keywords

Attempted Suicide Short Intervention Program, Acceptance and Commitment Therapy, Suicidal Ideation, Mental Pain, Suicide attempt, ASSIP, ACT

Brief summary

This is a randomized controlled trial that aims to compare the effectiveness of two psychological treatment approaches: the Attempted Suicide Short Intervention Program (ASSIP) and Acceptance and Commitment Therapy (ACT). The study seeks to determine which of these two methods is more effective in reducing suicidal ideation and mental pain in individuals who have recently attempted suicide. In this study, 60 participants with a history of suicide attempts will be randomly assigned to three groups. One group will receive ASSIP in addition to treatment as usual (TAU), the second group will receive ACT alongside TAU, and the third group will be a control group receiving TAU only. The results will be assessed using the Beck Scale for Suicide Ideation (BSSI) and the Orbach & Mikulincer Mental Pain Scale (OMMP) at three stages: pre-test, post-test, and follow-up. The ultimate goal of this research is to provide valuable insights into the comparative effectiveness of ASSIP and ACT interventions for suicide attempters and to contribute to evidence-based suicide prevention strategies. The findings are expected to inform clinical practice and guide future research in this field.

Detailed description

Background and Rationale: Suicide attempts are a major global public health concern and one of the leading causes of premature mortality, particularly among individuals aged 15 to 29 years. In Iran, as in many countries, suicide attempts represent a critical mental health issue requiring effective, evidence-based interventions. Two therapeutic approaches have demonstrated promising results in reducing suicidal ideation and preventing repeated attempts: the Attempted Suicide Short Intervention Program (ASSIP) and Acceptance and Commitment Therapy (ACT). ASSIP is a brief, structured, narrative-based intervention developed to address the underlying personal crisis and cognitive-behavioral mechanisms that lead to suicidal behavior. It typically involves three to four sessions, followed by long-term follow-up contacts. ACT is a third-wave behavioral therapy aimed at increasing psychological flexibility and reducing experiential avoidance, often associated with suicidal crises. Despite evidence supporting both methods internationally, little research has compared their effectiveness in the Iranian context. Study Overview: This randomized controlled trial will enroll 60 adults with a recent history of suicide attempt, identified through the Eslamshahr Health Network. Participants will be randomly assigned to one of three groups: 1. ASSIP plus treatment as usual (TAU) 2. ACT plus TAU 3. TAU only (control) Interventions will be delivered in an outpatient health center setting. The ASSIP group will receive three core sessions (with a possible fourth session) delivered according to the official ASSIP manual. The ACT group will receive four to five individual sessions following the ACT for Life protocol, specifically adapted for suicide prevention. Assessment and Follow-up: The primary outcomes are suicidal ideation and mental pain, assessed using validated Persian versions of the Beck Scale for Suicide Ideation (BSSI) and the Orbach & Mikulincer Mental Pain Scale (OMMP). Assessments will occur at baseline (pre-test), immediately after treatment (post-test), and one month after intervention (follow-up). Data will be analyzed using SPSS v27, applying descriptive statistics, analysis of covariance, and post hoc comparisons. Significance: This study is expected to generate context-specific evidence on the comparative effectiveness of ASSIP and ACT in reducing suicidal ideation and mental (or psychological) pain in Iranian suicide attempters. The findings will help inform mental health services in Iran and contribute to global suicide prevention strategies by clarifying which short-term, evidence-based intervention is more effective and feasible in similar healthcare settings.

Interventions

This is a brief, structured, patient-centered therapy consisting of three to four face-to-face sessions. Each session typically lasts between 60 to 90 minutes. A fourth session may be added if clinically necessary.

BEHAVIORALAcceptance and Commitment Therapy (ACT)

This intervention uses the ACT for Life protocol, which is designed to maximize recovery after suicidal crises. It consists of three components delivered over three to six individual sessions. The average number of sessions is four to five, with each session lasting approximately 60 minutes.

OTHERTreatment as Usual (TAU)

Treatment as usual (TAU) is not a structured intervention within this study. It may include standard outpatient or inpatient services, pharmacotherapy, or no structured treatment, depending on individual circumstances.

Sponsors

Ardakan University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)

Masking description

Only participants will be unaware of their group assignment.

Intervention model description

This study is a randomized controlled trial with three parallel groups. Participants will be randomly assigned to one of these three groups. The first group will receive ASSIP alongside treatment as usual (TAU) , the second group will receive ACT alongside TAU , and the third group (the control group) will receive only TAU. All groups will receive their interventions simultaneously and in parallel for the duration of the study.

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Being 18 years of age or older * Having the ability to read and write * Providing informed consent to participate in the study * Having at least one suicide attempt in the past 4 months

Exclusion criteria

* Having a severe psychiatric or physical illness that interferes with the treatment process * Receiving concurrent structured psychological interventions (other than TAU) that may interfere with the study's treatment process. * Lack of informed consent to participate in the study * Substance abuse based on DSM-5 criteria

Design outcomes

Primary

MeasureTime frameDescription
Mental Painpre-intervention, immediately following the intervention, and at 1-month follow-upThis measure assesses the intensity of mental pain using the 44-item Orbach & Mikulincer Mental Pain Scale (OMMP). The scale has nine subscales to measure various aspects of mental pain, including inevitability, lack of control, narcissism/worthlessness, emotional turmoil, numbness, alienation, confusion, social withdrawal, and emptiness (meaninglessness).
Suicidal Ideationpre-intervention, immediately following the intervention, and at 1-month follow-upThis measure assesses suicidal thoughts, attitudes, and behaviors using the 19-item self-report Beck Scale for Suicide Ideation (BSSI). Each item is rated on a Likert scale from 0 to 2, with a total score ranging from 0 to 38. A score of 0-5 indicates no suicidal ideation, 6-19 suggests the presence of suicidal thoughts, and 20-38 signifies a high level of suicide ideation and planning.

Countries

Iran

Contacts

Primary ContactHadiseh Yaghoobi, MA Student
yaghoobih98@gmail.com+98 9913338890
Backup ContactAzadeh Choobforoushzadeh, PhD
azadechoobforoush@ardakan.ac.ir+98 9127025535

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 3, 2026