Familial Mediterranean Fever
Conditions
Brief summary
Familial mediterranean fever (FMF) is common in mediterranean region. this disorder is connected with deterioration in functional performance, fitness of cardiorespiration, muscle strength, and bone mass
Detailed description
Familial mediterranean fever (FMF adolescent girls ) will be collected to be cateogarized to vibration group (vibration group) or control grouping. every group OF FMF will contain 20 FMF adolescent girls. both groups will receive vitamin D and their traditional colchicine doses daily for six months. vibration group will receive three sessions of 20-min whole body vibration in the week for 6 months
Interventions
OTHERwhole body vibration plus usual care
Familial mediterranean fever (20 FMF adolescent girls ) will be in this vibration group who will receive vitamin D and their traditional colchicine doses daily for six months. vibration group will also receive three sessions of 20-min whole body vibration in the week for 6 months
OTHERusual care
Familial mediterranean fever (20 FMF adolescent girls ) will be in this control group who will receive vitamin D and their traditional colchicine doses daily for six months.
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
FEMALE
Age
13 Years to 17 Years
Healthy volunteers
No
Inclusion criteria
FMF adolecent girls ages 13 -17 years forty patients
Exclusion criteria
cardiac problems renal problems liver problems diabetes brain problems
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| bone mineral density | it will be measured after 6 months | it is a measure for bone density at 2-4 lumbar vertebrae |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| vitamin D | it will be measured after 6 months | it will measured in plasma as serum 25-hydroxyvitamin D |
| osteoprotegerin | it will be measured after 6 months | it will measured in plasma |
| quadriceps torque | it will be measured after 6 months | it will measured in dominant side |
| z score | it will be measured after 6 months | it is a score for measure for bone mass at 2-4 lumbar vertebrae |
| Thirty second sit to stand test | it will be measured after 6 months | it is an indicator for functional performance |
| Ruffier index | it will be measured after 6 months | it is an indicator for cardiorespirtory fittness |
| Standing long jump test | it will be measured after 6 months | it is an indicator for functional performance |
Countries
Egypt
Contacts
Primary ContactAli MA Ismail, lecturer
Backup ContactAli Ismail
Outcome results
None listed