Familial Mediterranean Fever
Conditions
Brief summary
Familial mediterranean fever (FMF) is common to be diagnosed before age of 18 . this disorder is connected with deterioration in exercise tolerance, pulmonary capacities, fatigue tolerance,
Detailed description
Familial mediterranean fever (FMF adolescents ) will be collected to be cateogarized to inspiratory muscle retraining group (IMR group) or control waitlist grouping. every group OF FMF will contain 20 FMF adolescents. IMR group will receive two IMR sessions daily, five times weekly, for eight weeks (every IMR session will contain 3 sets of IMR and the set will contain 10 breath cycles).. both groups will receive their prescribed colchicine medications daily
Interventions
OTHERinspiratory muscle retraining
Familial mediterranean fever (FMF adolescents ) will be inspiratory muscle retraining group (IMR group) that will contain 20 FMF adolescents. IMR group will receive two IMR sessions daily, five times weekly, for eight weeks (every IMR session will contain 3 sets of IMR and the set will contain 10 breath cycles).. this group will receive their prescribed colchicine medications daily
OTHERcolchicine only
Familial mediterranean fever (FMF adolescents ) will be collected in this group OF FMF that will contain 20 FMF adolescents. this group will receive their prescribed colchicine medications daily for eight weeks
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
13 Years to 17 Years
Healthy volunteers
No
Inclusion criteria
* FMF adolecents * ages 13 -17 years * forty patients
Exclusion criteria
* cardiac problems * renal problems * liver problems * diabetes * brain problems
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Multidimensional Scale of Fatigue extracted from total score of pediatric quality of life | it will be measured after 8 weeks | it will assess fatigue perception |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| sleep and rest fatigue subscale of Multidimensional Scale of Fatigue related pediatric quality of life | it will be measured after 8 weeks | it will assess fatigue perception during sleep and rest |
| general fatigue subscale of Multidimensional Scale of Fatigue related pediatric quality of life | it will be measured after 8 weeks | it will assess general fatigue perception |
| six minute walk distance | it will be measured after 8 weeks | it will assess distance covered by FMF patients in six minutes of ongoing walking |
| Forced vital capacity | it will be measured after 8 weeks | it is a pulmonary capacity test |
| cognitive fatigue subscale of Multidimensional Scale of Fatigue related pediatric quality of life | it will be measured after 8 weeks | it will assess cognitive fatigue perception |
| Ration of Forced exhalation volume (at first second of exhalation) to forced exhalation capacity | it will be measured after 8 weeks | it is a pulmonary function testing |
| maximum inhalation pressure | it will be measured after 8 weeks | it is indicator for inspiratory muscular strength |
| physical sum of child health qestionnaire | it will be measured after 8 weeks | it is an indiactor for physical quality of life |
| mental sum of child health qestionnaire | it will be measured after 8 weeks | it is an indiactor for mental quality of life |
| Forced exhalation volume (at first second of exhalation) | it will be measured after 8 weeks | it is a pulmonary function testing |
Countries
Egypt
Contacts
Primary ContactAli MA Ismail, lecturer
Backup ContactIsmail, lecturer
Outcome results
None listed