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Therapeutic Exercises for Pain and Disability in Knee Osteoarthritis

Effectiveness of Therapeutic Exercises in Reducing Pain and Disability in Knee Osteoarthritis Patients in Older Adults

Status
Not yet recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07128875
Acronym
OA
Enrollment
56
Registered
2025-08-19
Start date
2025-08-17
Completion date
2026-07-17
Last updated
2025-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Osteoarthritis

Keywords

Osteoarthritis, Knee Pain, Therapeutic Exercise

Brief summary

This study aims to evaluate the effectiveness of structured therapeutic exercises in reducing pain and disability among older adults diagnosed with knee osteoarthritis. The intervention will involve a supervised physical therapy program targeting muscle strength, joint mobility, and functional capacity. Participants will undergo 6 weeks of therapy, and improvements in pain and physical function will be measured using validated scales.

Detailed description

Knee osteoarthritis (OA) is a leading cause of chronic pain and mobility limitations in the elderly population. Therapeutic exercises play a significant role in managing OA symptoms by strengthening the quadriceps, improving joint flexibility, and reducing stiffness. This study will enroll 60 participants aged 50-75 years diagnosed with knee OA. They will undergo a combination of strengthening, range of motion (ROM), and stretching exercises tailored to their condition. The intervention also includes adjunctive modalities such as hot pack and TENS to reduce pain and facilitate muscle engagement. Outcome measures will assess pain intensity, functional ability, and lower limb endurance before and after the intervention.

Interventions

OTHERExercise + TENS + Hot Pack

Therapeutic Exercises with Hot Pack and TENS This intervention focuses on improving physical function and reducing pain through structured therapeutic exercises for knee OA patients. The program includes Warm-Up (10 min): Light walking or stationary cycling. 2. Range of Motion (ROM) Exercises: Heel slides, seated knee flexion/extension. 3. Strengthening Exercises: Quadriceps sets Straight leg raises Mini squats (pain-free range) Seated knee extensions with resistance band 4. Stretching Exercises: Hamstring stretch Calf stretch Quadriceps stretch 5. Cool Down (5-10 min): Breathing and relaxation. 6. Hot Pack (15 min) + TENS (10 min): Applied pre and post exercises for pain relief and muscle relaxation.

OTHERExercise

Warm-Up (10 min): Light walking or stationary cycling. 2. Range of Motion (ROM) Exercises: Heel slides, seated knee flexion/extension. 3. Strengthening Exercises: Quadriceps sets Straight leg raises Mini squats (pain-free range) Seated knee extensions with resistance band 4. Stretching Exercises: Hamstring stretch Calf stretch Quadriceps stretch 5.

Sponsors

Riphah International University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)

Masking description

A triple-blind protocol was implemented. Participants with knee osteoarthritis, treating therapists, and outcome assessors were blinded to group assignments. Sham procedures were used in the control group to mimic the active treatment without therapeutic effect. Blinding integrity was periodically assessed through questionnaires evaluating participants' and assessors' guesses regarding group allocation.

Intervention model description

Group A Therapeutic Group

Eligibility

Sex/Gender
ALL
Age
35 Years to 40 Years
Healthy volunteers
No

Inclusion criteria

Minimum Age: 50 Years Maximum Age: 75 Years Sex: All Accepts Healthy Volunteers: No Inclusion Criteria: * Diagnosed with knee OA * Aged 50-75 years * Experiencing pain or functional limitation * Able to attend supervised sessions * Provided informed consent

Exclusion criteria

- History of total knee replacement * Severe cardiovascular or neurological conditions * Acute injury or fracture in lower limb * Uncontrolled hypertension or diabetes

Design outcomes

Primary

MeasureTime frameDescription
Pain Intensity6 MonthsPain intensity will be assessed using the Visual Analog Scale (VAS), which ranges from 0 to 10, where 0 indicates no pain and 10 indicates the worst imaginable pain. Higher scores represent worse outcomes.

Secondary

MeasureTime frameDescription
Change in Physical Disability6monthsPhysical disability will be measured using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). The WOMAC consists of 24 items scored from 0 (none) to 4 (extreme), yielding a total score range from 0 to 96, where higher scores indicate worse disability

Countries

Pakistan

Contacts

Primary ContactDr.Nadeem Ahmad, MS
n.ahmad@riphah.edu.pk03451915105
Backup ContactDr.Nadeem Ahmad, MS
drnadeem765@gmail.com03028367237

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026