Aerobic Capacity, Aerobic Exercise, Cardiopulmonary Exercise Test, Heart Failure
Conditions
Keywords
cardiopulmonary exercise test, aerobic capacity, aerobic exercise, heart failure
Brief summary
The goal of this observational study is to learn about the short-term effects of aerobic exercise in heart failure patients who were given exercise prescription with cardiopulmonary exercise stres test acocording to aerobic capacity . The main question it aims to answer is: Does aerobic exercise increase aerobic capacity and quality of life Participants already taking aerobic capacity as part of their regular medical care for Heart failure will asses with cardiopulmonary exercise test and clinical questionaries about quality of life and depression-anxiety level before and after aerobic exercise treatment .
Detailed description
The goal of this observational study is to learn about the short-term effects of aerobic exercise in heart failure patients who were given exercise prescription with cardiopulmonary exercise stres test acocording to aerobic capacity . The main question it aims to answer is: Does aerobic exercise increase aerobic capacity and quality of life Participants already taking aerobic capacity as part of their regular medical care for Heart failure will asses with cardiopulmonary exercise test and clinical questionaries about quality of life and depression-anxiety level before and after aerobic exercise treatment .
Interventions
OTHERAerobic exercise
continuous, moderate intencity aerobic exercise, 3 days a week, 30 minutes per day, 150/min per week for a total of 6 weeks
Sponsors
Ankara City Hospital Bilkent
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* Age 18-75, * Diagnosed with compensated HF, * BMI 18-30 kg/m², * LVEF \< 0.4, * NYHA 2-3, * Clinical symptoms have been stable for at least 2 weeks, and the dose of angiotensin-converting enzyme inhibitor/angiotensin receptor antagonist/angiotensin receptor inhibitor, beta-blocker, aldosterone inhibitor, and other drugs has been stable for at least 2 weeks.
Exclusion criteria
* History of a heart implant device within the last 6 weeks or a heart implant device or heart transplant plan within the next 12 months, * Acute coronary syndrome within the last 6 weeks, severe valvular heart disease, congenital heart disease, severe hypertrophic obstructive cardiomyopathy, acute myocarditis/pericarditis, intracardiac thrombosis, primary pulmonary hypertension, * Uncontrolled hypertension (systolic blood pressure \>200 mmHg and/or diastolic blood pressure \>110 mmHg), * Severe arrhythmias such as ventricular tachycardia, frequent multisource premature ventricular beats, high atrioventricular block, and significant QT interval prolongation during exercise testing, * Progressive dyspnea or * Loss of exercise endurance at rest within the last 3-5 days under low-intensity exercise load (\<2 MET) who have suffered myocardial ischemia, * Patients with cognitive impairment.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| cardiopulmonary exercise test results | 6 weeks | Cardiovascular responses: VO2 max value (ml/kg/dk) |
| cardiovascular exercise test result: Gas exchange parameters: | 6 weeks | PETCO₂ (partial end-tidal carbon dioxide), kilopascal |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Short Form (36) Health Scale | 6 weeks | Short Form (36) Health Scale Description: The SF-36 is a widely used, patient-reported survey of health status designed to assess overall health-related quality of life. It evaluates physical and mental health across multiple dimensions and is commonly used in clinical research and health outcomes studies. Domains Assessed (8 Subscales): Physical Functioning , Role Limitations due to Physical Health,Pain, General Health Perceptions Vitality, Social Functioning, Role Limitations due to Emotional Problems, Mental Health These can also be summarized into two main component scores: Physical Component Summary (PCS) Mental Component Summary (MCS) Scoring Range: Each subscale is scored from 0 to 100. 0 represents the worst possible health status; 100 represents the best possible health status. Interpretation of Scores: Higher scores indicate better health outcomes and higher quality of life, lower scores reflect poorer perceived healt |
| Hospital Anxiety and Depression Scale | 6 weeks | The Hospital Anxiety and Depression Scale (HADS) is a self-assessment tool developed to detect states of anxiety and depression in patients in non-psychiatric hospital clinics. It is widely used in both clinical practice and research settings to screen for emotional distress, especially in individuals with physical illnesses. Structure: The scale consists of 14 items, divided into two subscales: HADS-A (Anxiety) - 7 items HADS-D (Depression) - 7 items Each item assesses symptoms experienced over the past week. Scoring Range: Each item is scored from 0 to 3. Subscale scores range from 0 to 21 for both anxiety and depression. Interpretation of Scores (per subscale): 0-7: Normal 8-10: Borderline abnormal (mild) 11-21: Abnormal (clinically significant) Direction of Scores: Higher scores indicate greater severity of anxiety or depression symptoms. Lower scores suggest fewer or no symptoms. |
Countries
Turkey (Türkiye)
Outcome results
None listed