Bariatric Surgery, Obese Adolescents
Conditions
Keywords
bariatric surgery, obesity, modafinil, recovery from anethesia
Brief summary
study Effects of Preoperative Modafinil on Recovery Profile of Morbidly Obese Patients Scheduled for Bariatric Surgery if it Can Enhance Recovery From Anesthesia and provide improvement in recovery
Detailed description
The study was conducted to 20 patients scheduled for bariatric surgeries. The study group (Modafinil group) received oral 200 mg modafinil 8 hours before surgery and then another 200 mg 2 hours before surgery. The other group (Placebo group) were given placebo through the same regimen as Modafinil. Immediate recovery time, cognitive recovery, emotional (general) status, discharge from PACU according to modified Aldrete score were assessed.
Interventions
DRUGModafinil
dose of modafinil preoperatively for for active comparator
Sponsors
Ain Shams University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Subject, Caregiver)
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
1. Patients aged from 18 to 60 years. 2. Patients ASA II or III undergoing elective bariatric surgery. 3. BMI 30-50 kg/m2.
Exclusion criteria
1. Patient's refusal. 2. Age below 18 or above 60y. 3. History of cardiac disease. 4. History or known allergy to Modafinil. 5. Underlying liver or renal failure. 6. Chronic neurological or psychiatric condition. 7. Hemodynamically unstable patients. 8. History of drug dependance. 9. Habitual coffee consumption exceeding 2 cups per day.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| both groups were assessed as regard incidence of enhancement of immediate and cognitive recovery Comparison between groups as regard words recall as part of cognitive recovery data. | 1 day | Groups were compared in the primary outcome of our work (immediate recovery data) in OR by time intervals (T1, T2, T3 and T4) Comparison between groups as regard orientation as part of cognitive recovery score |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| assessment of difference of general and emotional status between both patients groups postoperatively | 24 hours | Groups were compared in assessment of general status and emotion and assessment of modified Aldrete score in PACU and compare between both groups |
Countries
Egypt
Outcome results
None listed