Skip to content

Lip Reduction Surgery for Port-wine Macrocheilia

Lip Reduction Surgery for Port-wine Macrocheilia: a Retrospective Single-center Clinical Study

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07128459
Acronym
macrocheilia
Enrollment
60
Registered
2025-08-19
Start date
2020-01-01
Completion date
2025-07-31
Last updated
2025-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Port Wine Stains

Brief summary

Patients with port-wine stains often develop macrocheilia, however, there is currently no effective treatment to significantly reduce the three-dimensional volume increase of the lips. This article presents a simplified five-step approach based on clinical experience, designed to assist inexperienced surgeons in performing this surgery effectively.

Interventions

PROCEDUREThe Five-Step lip reduction surgery

The Five-Step lip reduction surgery: (1) measurement and design; (2) incision and reduction of lip volume; (3) fixation and shape of the dry lip; (4) fixation and shape of the skin (the SMISS approach); (5) shaping of the wet lip mucosa (the SMISS approach).

Sponsors

Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
3 Years to 70 Years
Healthy volunteers
No

Inclusion criteria

1. Patients with port-wine macrocheilia. 2. Patients that underwent lip reduction surgery. 3. Age at surgery: ≥3 years and ≤70 years.

Exclusion criteria

1. Patients without port-wine macrocheilia. 2. Missing/incomplete baseline patient information. 3. Patients without postoperative photographs.

Design outcomes

Primary

MeasureTime frame
the Visual Analog ScaleFrom enrollment to the end of treatment in 6 months to one year

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026